DSpace DSpace UPC
 Català   Castellano   English  

E-prints UPC >
Altres >
Enviament des de DRAC >

Empreu aquest identificador per citar o enllaçar aquest ítem: http://hdl.handle.net/2117/9261

Ítem no disponible en accés obert per política de l'editorial

Arxiu Descripció MidaFormat
munozNova.pdfContinuum Mechanics ( Nova Publishers). Capítol:Stress dependent morphogenesis: continuum mechanics and system of trusses 212,05 kBAdobe PDF Accés restringit

Citació: Muñoz, José J.; Conte, V.; Miodownik, M. Stress dependent morphogenesis continuum mechanics and system of trusses. A: "Continuum mechanics". Nova Publishers, 2010, p. 223-243.
Títol: Stress dependent morphogenesis continuum mechanics and system of trusses
Autor: Muñoz Romero, José Veure Producció científica UPC; Conte, Vito; Miodownik, M.
Editorial: Nova Publishers
Data: 30-ago-2010
Tipus de document: Part of book or chapter of book
Resum: The mechanical analysis of soft tissues in biomechanics has undergone an increasing progress during the last decade. Part of this success is due to the development and application of some techniques of continuum mechanics, in particular, the decomposition of the deformation gradient, and the introduction of mass, density or volume changes in the reference configuration. Resorting to the common terminology employed in the literature, the changes in biomechanical processes may be classified as growth (change of mass), remodelling (change of density or other material properties such as fibre orientation) or morphogenesis (change of shape). Although the use of those concepts in bone and cardiovascular analysis is well extended, their use in morphogenesis during embryo development has been far less studied. The reasons of this fact may be found in the large shape changes encountered during this process, or the complexity of the material changes involved. In this chapter we develop a general framework for the modelling of morphogenesis by introducing a growth process in the structural elements of the cell, which in turn depends on the stress state of the tissue. Some experimental observations suggest this feedback mechanism during embryo development, and only very recently this behaviour has started to be simulated. We here derive the necessary equilibrium equations of a stress controlled growth mechanism in the context of continuum mechanics. In these derivations we assume a free energy source which is responsible of the active forces during the elongation process, and a passive hyperelastic response of the material. In addition, we write the necessary conditions that the active elongation law must satisfy in order to be thermodynamically consistent. We particularise these equations and conditions for the relevant elements of the cytoskeleton, namely, microfilaments and microtubules. We apply themodel to simulate the shape changes observed during embryomorphogenesis in truss element. As a salient result, themodel reveals that by imposing boundary stress conditions, unbounded elongation would be obtained. Therefore, either prescribed displacements or cross-links between fibres are necessary to reach a homeostatic state.
ISBN: 978-1-60741-585-5
URI: http://hdl.handle.net/2117/9261
Versió de l'editor: https://www.novapublishers.com/catalog/product_info.php?products_id=10027
Apareix a les col·leccions:LaCàN - Laboratori de Càlcul Numèric. Capítols de llibre
Departaments de Matemàtica Aplicada. Capítols de llibre
Altres. Enviament des de DRAC
Comparteix:


Stats Mostra les estadístiques d'aquest ítem

SFX Query

Tots els drets reservats. Aquesta obra està protegida pels drets de propietat intel·lectual i industrial corresponents. Sense perjudici de les exempcions legals existents, queda prohibida la seva reproducció, distribució, comunicació pública o transformació sense l'autorització del titular dels drets.

Per a qualsevol ús que se'n vulgui fer no previst a la llei, dirigiu-vos a: sepi.bupc@upc.edu

 

Valid XHTML 1.0! Programari DSpace Copyright © 2002-2004 MIT and Hewlett-Packard Comentaris
Universitat Politècnica de Catalunya. Servei de Biblioteques, Publicacions i Arxius