Exploració per tema "N-methylation"

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    • Increasing avß3 selectivity of the anti-angiogenic drug cilengitide by N-methylation 

      Mas Moruno, Carlos; Beck, J.G.; Doedens, L.; Frank, A.O.; Marinelli, L.; Cosconati, S.; Novellino, E.; Kessler, H. (2011)
      Article
      Accés restringit per política de l'editorial
      Thumbnail image of graphical abstract A subtle change: Structural changes upon amide bond methylation improve the selectivity of the anti-angiogenic drug Cilengitide, which after N-methylation at distinct positions ...