Exploració per tema "Mutació (Biologia)"
Ara es mostren els items 1-4 de 4
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Docking-based modeling of protein-protein interfaces for extensive structural and functional characterization of missense mutations
(Public Library of Science, 2017-08-25)
Article
Accés obertNext-generation sequencing (NGS) technologies are providing genomic information for an increasing number of healthy individuals and patient populations. In the context of the large amount of generated genomic data that is ... -
ICO amplicon NGS data analysis: a web tool for variant detection in common high-risk hereditary cancer genes analyzed by amplicon GS junior next-Generation Sequencing
(2013-11-01)
Article
Accés restringit per política de l'editorialNext-generation sequencing (NGS) has revolutionized genomic research and is set to have a major impact on genetic diagnostics thanks to the advent of benchtop sequencers and flexible kits for targeted libraries. Among the ... -
Influence of cholesterol on the orientation of the farnesylated GTP-bound KRas-4B binding with anionic model membranes
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-11-22)
Article
Accés obertThe Ras family of proteins is tethered to the inner leaflet of the cell membranes which plays an essential role in signal transduction pathways that promote cellular proliferation, survival, growth, and differentiation. ... -
PMut2: a web-based tool for predicting pathological mutations on proteins
(Barcelona Supercomputing Center, 2015-05-05)
Text en actes de congrés
Accés obertAmino acid substitutions in proteins can result in an altered phenotype which might lead to a disease. PMut2 is a method that can predict whether a mutation has a pathological effect on the protein function. It uses current ...