Exploració per tema "Medicaments -- Desenvolupament"
Ara es mostren els items 1-6 de 6
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B2D2- La integración de las técnicas biofísicas en el descubrimiento de fármacos
(2008-07-16)
Article
Accés obert -
Drug2ways: Reasoning over causal paths in biological networks for drug discovery
(2020-12-02)
Article
Accés obertElucidating the causal mechanisms responsible for disease can reveal potential therapeutic targets for pharmacological intervention and, accordingly, guide drug repositioning and discovery. In essence, the topology of a ... -
Identification of a novel inhibitory allosteric site of MAP kinases
(2016-11-29)
Article
Accés obertIn the present study, we report the discovery of a novel allosteric inhibitory site for p38a, a subclass of the mitogen-activated protein kinases (MAPK) family. The putative site was discovered after inspection of the ... -
Implementation of an internal coordinates anisotropic network model in PELE
(Barcelona Supercomputing Center, 2015-05-05)
Text en actes de congrés
Accés obertThe use of computational methods to elucidate the ligand-protein binding mechanisms is of utmost importance for the pharmaceutical industry. PELE (Protein Energy Landscape Exploration) software has proved to have ... -
Network community cluster-based analysis for the identification of potential leukemia drug targets
(Springer, 2019)
Comunicació de congrés
Accés obertLeukemia is a hematologic cancer which develops in blood tissue and causes rapid generation of immature and abnormal-shaped white blood cells. It is one of the most prominent causes of death in both men and women for which ... -
Study of the fluid dynamics during the depressurization step in the DELOS-susp process
(Universitat Politècnica de Catalunya, 2019-10-31)
Projecte Final de Màster Oficial
Accés obertEl grup NANOMOL, ICMAB-CSIC, juntament amb l'Spin-Off Nanomol Technologies, han desenvolupat un mètode de producció de nanovesícules d'una sola etapa per a aplicacions terapèutiques. Aquests sistemes vesiculats, tot i que ...