• Inhibition of deleterious chronic wound enzymes with plant polyphenols 

      Díaz González, María; Rocasalbas Lozano, Guillem; Francesko, Antonio; Touriño Eirín, Sonia; Torres, Josep Lluis; Tzanov, Tzanko (2012-01-18)
      Article
      Accés restringit per política de l'editorial
      The chronic wound environment is characterized by high concentrations of reactive oxygen species (ROS) and elevated levels of myeloperoxidase (MPO) and collagenases, together impairing the healing process. Therefore, the ...
    • Lignin-based nanoparticles as both structural and active elements in self-assembling and self-healing multifunctional hydrogels for chronic wound management 

      Morena Gatius, Ángela Gala; Pérez Rafael, Silvia; Tzanov, Tzanko (Multidisciplinary Digital Publishing Institute (MDPI), 2022-11-30)
      Article
      Accés obert
      Efficient wound healing is feasible when the dressing materials simultaneously target multiple factors causing wound chronicity, such as deleterious proteolytic and oxidative enzymes and bacterial infection. Herein, entirely ...
    • Lignin–cobalt nano-enabled poly(pseudo)rotaxane supramolecular hydrogel for treating chronic wounds 

      Crivello, Giulia; Orlandini, Giuliana; Morena, Angela Gala; Torchio, Alessandro; Mattu, Clara; Boffito, Monica; Tzanov, Tzanko; Ciardelli, Gianluca (Multidisciplinary Digital Publishing Institute (MDPI), 2023-06-13)
      Article
      Accés obert
      Chronic wounds (CWs) are a growing issue for the health care system. Their treatment requires a synergic approach to reduce both inflammation and the bacterial burden. In this work, a promising system for treating CWs was ...
    • Nanoparticle-driven self-assembling injectable hydrogels provide a multi-factorial approach for chronic wound treatment 

      Pérez Rafael, Silvia; Ivanova, Kristina Dimitrova; Stefanov, Ivaylo; Puiggalí Bellalta, Jordi; Valle Mendoza, Luis Javier del; Todorova, Katerina; Dimitrov, Petar; Hinojosa Caballero, Dolores; Tzanov, Tzanko (Elsevier, 2021-07-14)
      Article
      Accés obert
      Chronic wounds represent a major health burden and drain on medical system. Efficient wound repair is only possible if the dressing materials target simultaneously multiple factors involved in wound chronicity, such as ...
    • Polymeric composite dressings containing calcium-releasing nanoparticles accelerate wound healing in diabetic mice 

      Pérez Amodio, Soledad Graciela; Rubio, Nuria; Vila, Olaia; Navarro Requena, Claudia; Castaño, Óscar; Sanchez Ferrero, Aitor; Martí Muñoz, Joan; Alsina Gibert, Merce; Blanco Fernández, Jerónimo; Engel López, Elisabeth (2020-08-07)
      Article
      Accés obert
      Objective: Wound healing is a complex process that involves the interaction between different cell types and bioactive factors. Impaired wound healing is characterized by a loss in synchronization of these interactions, ...
    • Rapid colorimetric detection of wound infection with a fluidic paper device 

      Hoyo, Javier; Bassegoda Puigdomenech, Arnau; Ferreres Cabanes, Guillem; Hinojosa Caballero, Dolores; Gutierrez Capitan, Manuel; Baldi Coll, Antonio; Fernandez Sanchez, Cesar; Tzanov, Tzanko (Multidisciplinary Digital Publishing Institute (MDPI), 2022-08-15)
      Article
      Accés obert
      Current procedures for the assessment of chronic wound infection are time-consuming and require complex instruments and trained personnel. The incidence of chronic wounds worldwide, and the associated economic burden, urge ...