Exploració per autor "Rubio Martinez, Jaime"
Ara es mostren els items 1-3 de 3
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A step forward toward selective activation/inhibition of bak, a pro-apoptotic member of the Bcl-2 protein family: discovery of new prospective allosteric sites using molecular dynamics
Vila i Julià, Guillem; Pérez González, Juan Jesús; Rubio Martinez, Jaime (American Chemical Society, 2023-01-01)
Article
Accés restringit per política de l'editorialBak is a pro-apoptotic protein and a member of the Bcl-2 family that plays a key role in apoptosis, a programmed cell death mechanism of multicellular organisms. Its activation under death stimuli triggers the permeabilization ... -
Assessment of the bound conformation of bombesin to the BB1 and BB2 receptors
Vila i Julià, Guillem; Rubio Martinez, Jaime; Pérez González, Juan Jesús (Elsevier, 2024-01-01)
Article
Accés restringit per política de l'editorialBombesin is an endogenous peptide involved in a wide spectrum of physiological activities ranging from satiety, control of circadian rhythm and thermoregulation in the central nervous system, to stimulation of gastrointestinal ... -
Rational design of new class of BH3-mimetics as inhibitors of the Bcl-X(L) protein
Pinto Manresa, Marta; Orzaez, Maria del Mar; Delgado-Soler, L.; Pérez González, Juan Jesús; Rubio Martinez, Jaime (2011-06)
Article
Accés obertThe Bcl-2 family of proteins plays an important role in the intrinsic pathway of cell apoptosis. Overexpression of prosurvival members of this family of proteins is often associated with the development of many types of ...