Exploració per autor "Deco, Gustavo"

Ara es mostren els items 13-31 de 31

    • Increased sensitivity to strong perturbations in a whole-brain model of LSD 

      Jobst, Beatrice M.; Atasoy, Selen; Ponce Álvarez, Adrián Fernando; Sanjuan, Ana; Roseman, Leor; Kaelen, Mendel; Carhart-Harris, Robin; Kringelbach, Morten L.; Deco, Gustavo (2021-04-15)
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      Lysergic acid diethylamide (LSD) is a potent psychedelic drug, which has seen a revival in clinical and pharmacological research within recent years. Human neuroimaging studies have shown fundamental changes in brain-wide ...

    • Increased stability and breakdown of brain effective connectivity during slow-wave sleep: mechanistic insights from whole-brain computational modelling 

      Jobst, Beatrice M.; Hindriks, Rikkert; Laufs, Helmut; Tagliazucchi, Enzo; Hahn, Gerald; Ponce Álvarez, Adrián Fernando; Stevner, Angus B.A.; Kringelbach, Morten L.; Deco, Gustavo (Springer Nature, 2017-07-05)
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      Recent research has found that the human sleep cycle is characterised by changes in spatiotemporal patterns of brain activity. Yet, we are still missing a mechanistic explanation of the local neuronal dynamics underlying ...

    • Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics 

      López-González, Ane; Panda, Rajanikant; Ponce Álvarez, Adrián Fernando; Zamora-López, Gorka; Escrichs, Anira; Martial, Charlotte; Thibaut, Aurore; Gosseries, Olivia; Kringelbach, Morten L.; Annen, Jitka; Laureys, Steven; Deco, Gustavo (Springer Nature, 2021-09-06)
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      Low-level states of consciousness are characterized by disruptions of brain activity that sustain arousal and awareness. Yet, how structural, dynamical, local and network brain properties interplay in the different levels ...

    • Low entropy map of brain oscillatory activity identifies spatially localized events: A new method for automated epilepsy focus prediction 

      Principe, Alessandro; Tauste Campo, Adrián Francisco; Vila Vidal, Manel; Rocamora, Rodrigo; Deco, Gustavo; Pérez Enríquez, Carmen (2020-03)
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      The spatial mapping of localized events in brain activity critically depends on the correct identification of the pattern signatures associated with those events. For instance, in the context of epilepsy research, a number ...

    • LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics 

      Ruffini, Giulio; Damiani, Giada; Lozano-Soldevilla, Diego; Deco, Nikolas; Rosas, Fernando E.; Kiani, Narsis A.; Ponce Álvarez, Adrián Fernando; Kringelbach, Morten L.; Carhart-Harris, Robin; Deco, Gustavo (Public Library of Science (PLOS), 2023-02-03)
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      A topic of growing interest in computational neuroscience is the discovery of fundamental principles underlying global dynamics and the self-organization of the brain. In particular, the notion that the brain operates near ...

    • Macroscopic quantities of collective brain activity during wakefulness and anesthesia 

      Ponce Álvarez, Adrián Fernando; Uhrig, Lynn; Deco, Nikolas; Signorelli, Camilo M.; Kringelbach, Morten L.; Jarraya, Béchir; Deco, Gustavo (2022-01-15)
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      The study of states of arousal is key to understand the principles of consciousness. Yet, how different brain states emerge from the collective activity of brain regions remains unknown. Here, we studied the fMRI brain ...

    • Model-based whole-brain effective connectivity to study distributed cognition in health and disease 

      Tauste Campo, Adrián Francisco; Deco, Gustavo; Insabato, Andrea; Gilson, Matthieu; Zamora López, Gorka; Pallarés Picazo, Vicente; Adhikari, Mohit H.; Senden, Mario; Mantini, Dante; Corbetta, Maurizio (The MIT Press. Massachusetts Institute of Technology, 2020-01)
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      Neuroimaging techniques are now widely used to study human cognition. The functional associations between brain areas have become a standard proxy to describe how cognitive processes are distributed across the brain network. ...

    • Multi-stable perception balances stability and sensitivity 

      Pastukhov, Alexander; Garcia Rodriguez, Pedro E.; Haenicke, Joachim; Guillamon Grabolosa, Antoni; Deco, Gustavo; Braun, Jochen (2013)
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      We report that multi-stable perception operates in a consistent, dynamical regime, balancing the conflicting goals of stability and sensitivity. When a multi-stable visual display is viewed continuously, its phenomenal ...

    • One ring to rule them all: the unifying role of prefrontal cortex in steering task-related brain dynamics 

      Deco, Gustavo; Sanz Perl, Yonatan; Ponce Álvarez, Adrián Fernando; Tagliazucchi, Enzo; Whybrow, Peter C; Fuster, Joaquín; Kringelbach, Morten L. (2023-08)
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      Surviving and thriving in a complex world require intricate balancing of higher order brain functions with essential survival-related behaviours. Exactly how this is achieved is not fully understood but a large body of ...

    • Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations 

      Deco, Gustavo; Ponce Álvarez, Adrián Fernando; Mantini, Dante; Romani, Gian Luca; Hagmann, Patrick; Corbetta, Maurizio (2013-07-03)
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      Brain fluctuations at rest are not random but are structured in spatial patterns of correlated activity across different brain areas. The question of how resting-state functional connectivity (FC) emerges from the brain's ...

    • Resting-state temporal synchronization networks emerge from connectivity topology and heterogeneity 

      Ponce Álvarez, Adrián Fernando; Deco, Gustavo; Hagmann, Patrick; Romani, Gian Luca; Mantini, Dante; Corbetta, Maurizio (Public Library of Science (PLOS), 2015-02-18)
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      Spatial patterns of coherent activity across different brain areas have been identified during the resting-state fluctuations of the brain. However, recent studies indicate that resting-state activity is not stationary, ...

    • Spontaneous cortical activity is transiently poised close to criticality 

      Hahn, Gerald; Ponce Álvarez, Adrián Fernando; Monier, Cyril; Benvenuti, Giacomo; Kumar, Arvind; Chavane, Frédéric; Deco, Gustavo; Frégnac, Yves (Public Library of Science (PLOS), 2017-05-24)
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      Brain activity displays a large repertoire of dynamics across the sleep-wake cycle and even during anesthesia. It was suggested that criticality could serve as a unifying principle underlying the diversity of dynamics. ...

    • Stimulus-dependent variability and noise correlations in cortical MT neurons 

      Ponce Álvarez, Adrián Fernando; Thiele, Alexander; Albright, Thomas D.; Stoner, Gene R.; Deco, Gustavo (International Academy of Sciences (NAS), 2013-08-06)
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      Population codes assume that neural systems represent sensory inputs through the firing rates of populations of differently tuned neurons. However, trial-by-trial variability and noise correlations are known to affect the ...

    • Synaptic depression and slow oscillatory activity in a biophysical network model of the cerebral cortex 

      Benita, Jose M.; Guillamon Grabolosa, Antoni; Deco, Gustavo; Sánchez-Vives, Maria V. (2012-08-28)
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      Short-termsynapticdepression(STD)isaformofsynapticplasticitythathasalargeimpactonnetworkcomputations.ExperimentalresultssuggestthatSTDismodulatedbycorticalactivity,decreasingwithactivityinthenetworkandincreasingduringsil ...

    • Task-driven activity reduces the cortical activity space of the brain: experiment and whole-brain modeling 

      Ponce Álvarez, Adrián Fernando; He, Biyu J; Hagmann, Patrick; Deco, Gustavo (Public Library of Science (PLOS), 2015-08-28)
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      How a stimulus or a task alters the spontaneous dynamics of the brain remains a fundamental open question in neuroscience. One of the most robust hallmarks of task/stimulus-driven brain dynamics is the decrease of variability ...

    • The emergence of spontaneous and evoked functional connectivity in a large-scale model of the brain 

      Ponce Álvarez, Adrián Fernando; Deco, Gustavo (Elsevier, 2015-02-24)
      Capítol de llibre
      Accés restringit per política de l'editorial
      We show how functional connectivity (FC) emerges in an anatomically constrained large-scale spiking model of the brain. To gain theoretical insights, we approximate the model, using a mean-field technique that leads to a ...

    • The Hopf whole-brain model and its linear approximation 

      Ponce Álvarez, Adrián Fernando; Deco, Gustavo (Springer Nature, 2024-01-31)
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      Whole-brain models have proven to be useful to understand the emergence of collective activity among neural populations or brain regions. These models combine connectivity matrices, or connectomes, with local node dynamics, ...

    • Using in silico perturbational approach to identify critical areas in schizophrenia 

      Vila Vidal, Manel; Kringelbach, Morten L.; Deco, Gustavo (2023-06-15)
      Article
      Accés restringit per política de l'editorial
      Schizophrenia is a debilitating neuropsychiatric disorder whose underlying correlates remain unclear despite decades of neuroimaging investigation. One contentious topic concerns the role of global signal (GS) fluctuations ...

    • Whole-brain neuronal activity displays crackling noise dynamics 

      Ponce Álvarez, Adrián Fernando; Jouary, Adrien; Privat, Martin; Deco, Gustavo; Sumbre, Germán (2018-12-19)
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      Previous studies suggest that the brain operates at a critical point in which phases of order and disorder coexist, producing emergent patterned dynamics at all scales and optimizing several brain functions. Here, we ...