Ara es mostren els items 3-22 de 30

    • Circuit mechanisms for the chemical modulation of cortex-wide network interactions and behavioral variability 

      Pfeffer, Thomas; Ponce Álvarez, Adrián Fernando; Tsetsos, Konstantinos; Meindertsma, Thomas; Gahnström, Christoffer Julius; van den Brink, Ruud Lucas; Nolte, Guido; Engel, Andreas Karl; Deco, Gustavo; Donner, Thobias Hinrich (2021-07-16)
      Article
      Accés obert
      Influential theories postulate distinct roles of catecholamines and acetylcholine in cognition and behavior. However, previous physiological work reported similar effects of these neuromodulators on the response properties ...
    • Cortical state transitions and stimulus response evolve along stiff and sloppy parameter dimensions, respectively 

      Ponce Álvarez, Adrián Fernando; Mochol, Gabriela; Hermoso-Mendizabal, Ainhoa; de la Rocha, Jaime; Deco, Gustavo (2020-03-17)
      Article
      Accés obert
      Previous research showed that spontaneous neuronal activity presents sloppiness: the collective behavior is strongly determined by a small number of parameter combinations, defined as ‘stiff’ dimensions, while it is ...
    • Critical scaling of whole-brain resting-state dynamics 

      Ponce Álvarez, Adrián Fernando; Kringelbach, Morten L.; Deco, Gustavo (Springer Nature, 2023-06-10)
      Article
      Accés obert
      Scale invariance is a characteristic of neural activity. How this property emerges from neural interactions remains a fundamental question. Here, we studied the relation between scale-invariant brain dynamics and structural ...
    • Degenerate time-dependent network dynamics anticipate seizures in human epileptic brain 

      Tauste Campo, Adrián Francisco; Principe, Alessandro; Rocamora, Rodrigo; Ley Nácher, Miguel; Deco, Gustavo (Public Library of Science (PLOS), 2018-04-05)
      Article
      Accés obert
      Epileptic seizures are known to follow specific changes in brain dynamics. While some algorithms can nowadays robustly detect these changes, a clear understanding of the mechanism bywhich these alterations occur and generate ...
    • Dinámica estocástica como principio de procesamiento en el cerebro 

      Deco, Gustavo (2010-05-05)
      Audiovisual
      Accés obert
    • Distinct modes of functional connectivity induced by movie-watching 

      Demirtas, Murat; Ponce Álvarez, Adrián Fernando; Gilson, Matthieu; Hagmann, Patrick; Mantini, Dante; Betti, Viviana; Romani, Gian Luca; Friston, Karl J.; Corbetta, Maurizio; Deco, Gustavo (2019-01-01)
      Article
      Accés obert
      A fundamental question in systems neuroscience is how endogenous neuronal activity self-organizes during particular brain states. Recent neuroimaging studies have demonstrated systematic relationships between resting-state ...
    • Estimation of directed effective connectivity from fMRI functional connectivity hints at asymmetries of cortical connectome 

      Gilson, Matthieu; Moreno-Bote, Rubén; Ponce Álvarez, Adrián Fernando; Ritter, Petra; Deco, Gustavo (Public Library of Science (PLOS), 2016-03-16)
      Article
      Accés obert
      The brain exhibits complex spatio-temporal patterns of activity. This phenomenon is governed by an interplay between the internal neural dynamics of cortical areas and their connectivity. Uncovering this complex relationship ...
    • Functional network antagonism and consciousness 

      Demertzi, Athena; Kucyi, Aaron; Ponce Álvarez, Adrián Fernando; Keliris, Georgios; Susan Whitfield-Gabrieli, Susan; Deco, Gustavo (The MIT Press. Massachusetts Institute of Technology, 2022-10-01)
      Article
      Accés obert
      Spontaneous brain activity changes across states of consciousness. A particular consciousness-mediated configuration is the anticorrelations between the default mode network and other brain regions. What this antagonistic ...
    • How local excitation-inhibition ratio impacts the whole brain dynamics 

      Deco, Gustavo; Ponce Álvarez, Adrián Fernando; Hagmann, Patrick; Romani, Gian Luca; Mantini, Dante; Corbetta, Maurizio (2014-06-04)
      Article
      Accés obert
      The spontaneous activity of the brain shows different features at different scales. On one hand, neuroimaging studies show that long-range correlations are highly structured in spatiotemporal patterns, known as resting-state ...
    • Increased sensitivity to strong perturbations in a whole-brain model of LSD 

      Jobst, Beatrice M.; Atasoy, Selen; Ponce Álvarez, Adrián Fernando; Sanjuan, Ana; Roseman, Leor; Kaelen, Mendel; Carhart-Harris, Robin; Kringelbach, Morten L.; Deco, Gustavo (2021-04-15)
      Article
      Accés obert
      Lysergic acid diethylamide (LSD) is a potent psychedelic drug, which has seen a revival in clinical and pharmacological research within recent years. Human neuroimaging studies have shown fundamental changes in brain-wide ...
    • Increased stability and breakdown of brain effective connectivity during slow-wave sleep: mechanistic insights from whole-brain computational modelling 

      Jobst, Beatrice M.; Hindriks, Rikkert; Laufs, Helmut; Tagliazucchi, Enzo; Hahn, Gerald; Ponce Álvarez, Adrián Fernando; Stevner, Angus B.A.; Kringelbach, Morten L.; Deco, Gustavo (Springer Nature, 2017-07-05)
      Article
      Accés obert
      Recent research has found that the human sleep cycle is characterised by changes in spatiotemporal patterns of brain activity. Yet, we are still missing a mechanistic explanation of the local neuronal dynamics underlying ...
    • Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics 

      López-González, Ane; Panda, Rajanikant; Ponce Álvarez, Adrián Fernando; Zamora-López, Gorka; Escrichs, Anira; Martial, Charlotte; Thibaut, Aurore; Gosseries, Olivia; Kringelbach, Morten L.; Annen, Jitka; Laureys, Steven; Deco, Gustavo (Springer Nature, 2021-09-06)
      Article
      Accés obert
      Low-level states of consciousness are characterized by disruptions of brain activity that sustain arousal and awareness. Yet, how structural, dynamical, local and network brain properties interplay in the different levels ...
    • Low entropy map of brain oscillatory activity identifies spatially localized events: A new method for automated epilepsy focus prediction 

      Principe, Alessandro; Tauste Campo, Adrián Francisco; Vila Vidal, Manel; Rocamora, Rodrigo; Deco, Gustavo; Pérez Enríquez, Carmen (2020-03)
      Article
      Accés obert
      The spatial mapping of localized events in brain activity critically depends on the correct identification of the pattern signatures associated with those events. For instance, in the context of epilepsy research, a number ...
    • LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics 

      Ruffini, Giulio; Damiani, Giada; Lozano-Soldevilla, Diego; Deco, Nikolas; Rosas, Fernando E.; Kiani, Narsis A.; Ponce Álvarez, Adrián Fernando; Kringelbach, Morten L.; Carhart-Harris, Robin; Deco, Gustavo (Public Library of Science (PLOS), 2023-02-03)
      Article
      Accés obert
      A topic of growing interest in computational neuroscience is the discovery of fundamental principles underlying global dynamics and the self-organization of the brain. In particular, the notion that the brain operates near ...
    • Macroscopic quantities of collective brain activity during wakefulness and anesthesia 

      Ponce Álvarez, Adrián Fernando; Uhrig, Lynn; Deco, Nikolas; Signorelli, Camilo M.; Kringelbach, Morten L.; Jarraya, Béchir; Deco, Gustavo (2022-01-15)
      Article
      Accés obert
      The study of states of arousal is key to understand the principles of consciousness. Yet, how different brain states emerge from the collective activity of brain regions remains unknown. Here, we studied the fMRI brain ...
    • Model-based whole-brain effective connectivity to study distributed cognition in health and disease 

      Tauste Campo, Adrián Francisco; Deco, Gustavo; Insabato, Andrea; Gilson, Matthieu; Zamora López, Gorka; Pallarés Picazo, Vicente; Adhikari, Mohit H.; Senden, Mario; Mantini, Dante; Corbetta, Maurizio (The MIT Press. Massachusetts Institute of Technology, 2020-01)
      Article
      Accés obert
      Neuroimaging techniques are now widely used to study human cognition. The functional associations between brain areas have become a standard proxy to describe how cognitive processes are distributed across the brain network. ...
    • Multi-stable perception balances stability and sensitivity 

      Pastukhov, Alexander; Garcia Rodriguez, Pedro E.; Haenicke, Joachim; Guillamon Grabolosa, Antoni; Deco, Gustavo; Braun, Jochen (2013)
      Article
      Accés obert
      We report that multi-stable perception operates in a consistent, dynamical regime, balancing the conflicting goals of stability and sensitivity. When a multi-stable visual display is viewed continuously, its phenomenal ...
    • One ring to rule them all: the unifying role of prefrontal cortex in steering task-related brain dynamics 

      Deco, Gustavo; Sanz Perl, Yonatan; Ponce Álvarez, Adrián Fernando; Tagliazucchi, Enzo; Whybrow, Peter C; Fuster, Joaquín; Kringelbach, Morten L. (2023-08)
      Article
      Accés obert
      Surviving and thriving in a complex world require intricate balancing of higher order brain functions with essential survival-related behaviours. Exactly how this is achieved is not fully understood but a large body of ...
    • Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations 

      Deco, Gustavo; Ponce Álvarez, Adrián Fernando; Mantini, Dante; Romani, Gian Luca; Hagmann, Patrick; Corbetta, Maurizio (2013-07-03)
      Article
      Accés obert
      Brain fluctuations at rest are not random but are structured in spatial patterns of correlated activity across different brain areas. The question of how resting-state functional connectivity (FC) emerges from the brain's ...
    • Resting-state temporal synchronization networks emerge from connectivity topology and heterogeneity 

      Ponce Álvarez, Adrián Fernando; Deco, Gustavo; Hagmann, Patrick; Romani, Gian Luca; Mantini, Dante; Corbetta, Maurizio (Public Library of Science (PLOS), 2015-02-18)
      Article
      Accés obert
      Spatial patterns of coherent activity across different brain areas have been identified during the resting-state fluctuations of the brain. However, recent studies indicate that resting-state activity is not stationary, ...