Exploració per autor "Céolin, René"
Ara es mostren els items 20-36 de 36
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Pitfalls and feedback when constructing topological pressure-temperature phase diagrams
Céolin, René; Toscani, Siro; Rietveld, Ivo B.; Barrio Casado, María del; Tamarit Mur, José Luis (2017-04-18)
Article
Accés obertThe stability hierarchy between different phases of a chemical compound can be accurately reproduced in a topological phase diagram. This type of phase diagrams may appear to be the result of simple extrapolations, however, ... -
Polymorphism of benzylthiouracil, an active pharmaceutical ingredient against hyperthyroidism
Rietveld, Ivo B.; Allouchi, Hassan; Barrio Casado, María del; Céolin, René; Tamarit Mur, José Luis (2021-04-01)
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Accés obertThe crystal structures of dimorphic benzylthiouracil, a drug against hyperthyroidism, have been redetermined and the atom coordinates of the two independent molecules of form I have been obtained for the first time. The ... -
Polymorphism of spironolactone: An unprecedented case of monotropy turning to enantiotropy with a huge difference in the melting temperatures
Rietveld, Ivo B.; Barrio Casado, María del; Lloveras Muntané, Pol Marcel; Céolin, René; Tamarit Mur, José Luis (2018-09-25)
Article
Accés obert -
Pressure-temperature phase diagram of the dimorphism of the anti-inflammatory drug nimesulide
Barrio Casado, María del; Huguet, Jordi; Robert, B.; Rietveld, Ivo B.; Céolin, René; Tamarit Mur, José Luis (2017-06-15)
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Accés obertUnderstanding the phase behavior of active pharmaceutical ingredients is important for formulations of dosage forms and regulatory reasons. Nimesulide is an anti-inflammatory drug that is known to exhibit dimorphism; however ... -
Pressure–temperature state diagram for the phase relationships between benfluorex hydrochloride forms I and II: A case of enantiotropic behavior
Barrio Casado, María del; Maccaroni, Elisabetta; Rietveld, Ivo B.; Macpezzi, Luciana; Masciocchi, Norberto; Céolin, René; Tamarit Mur, José Luis (2011-11-03)
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Accés restringit per política de l'editorialThe active pharmaceutical ingredient racemic benfluorex hydrochloride (benfluorex–HCl) has an interesting phase behavior due to an elusive solid–solid phase transition. The stability hierarchy between different phases is ... -
Rimonabant dimorphism and its pressure–temperature phasegiagram: A delicate case of overall monotropic behavior
Perrin, Marc-Antoine; Bauer, Michel; Barrio Casado, María del; Tamarit Mur, José Luis; Céolin, René; Rietveld, Ivo B. (2013-05-20)
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Accés restringit per política de l'editorialCrystalline polymorphism occurs frequently in the solid state of active pharmaceutical ingredients, and this is problematic for the development of a suitable dose form. Rimonabant, an active pharmaceutical ingredient ... -
Solid-state properties and dehydration behavior of the active pharmaceutical ingredient potassium guaiacol-4-sulfonate
Mahé, Nathalie; Nicolai, Beatrice; Barrio Casado, María del; Perrin, Marc Antoine; Do, Bernard; Tamarit Mur, José Luis; Céolin, René; Rietveld, Ivo B. (2013-05-20)
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Accés restringit per política de l'editorialPotassium guaiacolsulfonate is an active pharmaceutical ingredient that has been in use for more than a century, and it is still widely used in cough syrups. Nonetheless, no crystal structure has ever been determined to ... -
Stability hierarchy between Piracetam forms I, II, and III from experimental pressure–temperature diagrams and topological inferences
Toscani, Siro; Céolin, René; Ter Minassian, Leon; Barrio Casado, María del; Veglio, Néstor Raúl; Tamarit Mur, José Luis; Louër, Daniel; Rietveld, Ivo B. (2016-01-30)
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Accés obertThe trimorphism of the active pharmaceutical ingredient piracetam is a famous case of polymorphism that has been frequently revisited by many researchers. The phase relationships between forms I, II, and III were ambiguous ... -
The phase diagram of the API benzocaine and its highly persistent, metastable crystalline polymorphs
Rietveld, Ivo B.; Akiba, Hiroshi; Yamamuro, Osamu; Barrio Casado, María del; Céolin, René; Tamarit Mur, José Luis (Multidisciplinary Digital Publishing Institute (MDPI), 2023-05-20)
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Accés obertThe availability of sufficient amounts of form I of benzocaine has led to the investigation of its phase relationships with the other two existing forms, II and III, using adiabatic calorimetry, powder X-ray diffraction, ... -
The Pressure-temperature phase diagram of metacetamol and its comparison to the phase diagram of paracetamol
Barrio Casado, María del; Huguet, Judit; Rietveld, Ivo B.; Robert, Benoit; Céolin, René; Tamarit Mur, José Luis (2017-06-01)
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Accés obertUnderstanding the polymorphic behavior of active pharmaceutical ingredients is important for formulation purposes and regulatory reasons. Metacetamol is an isomer of paracetamol and it similarly exhibits polymorphism. In ... -
The relationship between orientational disorder and pressure: The case study of succinonitrile
Tamarit Mur, José Luis; Rietveld, Ivo B.; Barrio Casado, María del; Céolin, René (2014-12-25)
Article
Accés restringit per política de l'editorialPlastic phases can be considered as an intermediary state between the crystalline state and the liquid state, in which the molecules maintain their positions, but they exhibit orientational disorder. Whereas plastic phases ... -
The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt
Barrio Casado, María del; Céolin, René; Robert, Benoit; Allouchi, Hassan; Teulon, Jean-Marie; Guéchot, Christophe; Tamarit Mur, José Luis; Rietveld, Ivo B. (2021-12-15)
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Accés obertMorniflumate diniflumate, a molecular compound involving niflumic acid and its ß-morpholino ethyl ester (morniflumate) in the mole ratio 2:1, is found to crystallize in a triclinic P - 1 space group with a unit-cell volume ... -
Thermal expansion of L-ascorbic acid
Nicolaï, Béatrice; Barrio Casado, María del; Tamarit Mur, José Luis; Céolin, René; Rietveld, Ivo B. (2017-04-01)
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Accés obertThe specific volume of vitamin C has been investigated by X-ray powder diffraction as a function of temperature from 110¿K up to complete degradation around 440¿K. Its thermal expansion is relatively small in comparison ... -
Topological and experimental approach to the pressure-temperature-composition phase diagram of the binary enantiomer system d- and I-camphor
Rietveld, Ivo B.; Barrio Casado, María del; Espeau, Philippe; Tamarit Mur, José Luis; Céolin, René (2011-01-31)
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Accés restringit per política de l'editorialIn 1981, Jacques, Collet, and Wilen already put forward the idea to use pressure to influence equilibria in binary enantiomer systems in analogy with temperature (Jacques et al. Enantiomers, Racemates and Resolutions; John ... -
Uniaxial negative thermal expansion in crystals of tienoxolol
Nicolaï, Beatrice; Rietveld, Ivo B.; Barrio Casado, María del; Mahé, Nathalie; Tamarit Mur, José Luis; Céolin, René; Guéchot, Christophe; Teulon, Jean-Marie (2012-06-17)
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Accés restringit per política de l'editorialThe thermal expansion of tienoxolol has been investigated by X-ray powder diffraction up to its melting temperature. The data indicate that the expansion is anisotropic and even negative in one direction of the unit cell. ... -
Uniaxial negative thermal expansion in polymorphic 2-bromobenzophenone, due to aromatic interactions?
Romanini, Michela; Rietveld, Ivo B.; Barrio Casado, María del; Negrier, Philippe; Mondieig, Denise; Macovez, Roberto; Céolin, René; Tamarit Mur, José Luis (American Chemical Society, 2021-04-07)
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Accés obertThe structure of the metastable form II of 2-bromobenzophenone, obtained by crystallization from the melt, has been determined by powder X-ray diffraction. Form II has been solved in the centrosymmetric monoclinic space ... -
Van-der-Waals based solvates of C-60 with CBr2Cl2 and CBr2(CH3)(2)
Ye, Jin; Barrio Casado, María del; Céolin, René; Qureshi, Navid; Rietveld, Ivo B.; Tamarit Mur, José Luis (2016-09-30)
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Accés obertWe demonstrate that solvates of fullerene C60 form very predictable structures with finely tunable properties through the choice of the second component or solvent. Cubic co-crystals of C60·12CCl2Br2 and C60·12CBr2(CH3)2 ...