Exploració per autor "Brunel, Helena"
Ara es mostren els items 1-4 de 4
-
Next generation sequencing to dissect the genetic architecture of KNG1 and F11 loci using factor XI levels as an intermediate phenotype of thrombosis
Martin-Fernandez, Laura; Gavidia Bovadilla, Giovana Elizabeth; Corrales, Irene; Brunel, Helena; Ramirez, Lorena; Lopez Esteban, Sonia; Carlos Souto, Juan; Vidal, Francisco; Soria, José Manuel (2017-04-26)
Article
Accés obertVenous thromboembolism is a complex disease with a high heritability. There are significant associations among Factor XI (FXI) levels and SNPs in the KNG1 and F11 loci. Our aim was to identify the genetic variation of KNG1 ... -
Segmented Symbolic Dynamics for Risk Stratification in Patients with Ischemic Heart Failure, Cardiovascular Engineering and Technology
Voss, Andreas; Schroeder, Rico; Caminal Magrans, Pere; Vallverdú Ferrer, Montserrat; Brunel, Helena; Cygankiewicz, I.; Vázquez, Rafael; Bayes de Luna, Antonio (Springer, 2010-12-30)
Article
Accés restringit per política de l'editorialChronic heart failure (CHF) is recognized as major and escalating public health problem. Approximately 69% of CHF patients suffer from cardiac death within 5 years after the initial diagnosis. Until now, no generally accepted ... -
Solarius: an R interface to SOLAR for variance component analysis in pedigrees
Ziyatdinov, Andrey; Brunel, Helena; Martinez Perez, Angel; Buil, Alfonso; Perera Lluna, Alexandre; Soria, José Manuel (2016-02-15)
Article
Accés obertThe open source environment R is one of the most widely used software for statistical computing. It provides a variety of applications including statistical genetics. Most of the powerful tools for quantitative genetic ... -
The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes
Brunel, Helena; Massanet, Raimon; Martinez Perez, Angel; Ziyatdinov, Andrey; Martin-Fernandez, Laura; Souto, Juan Carlos; Perera Lluna, Alexandre; Soria, José Manuel (2016-12-22)
Article
Accés obertTraditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same ...