• Relaxation dynamics and frequency response of a noisy cell signaling network 

      Rue Queralt, Pau; Pons Rivero, Antonio Javier; Domedel Puig, Núria; García Ojalvo, Jordi (2010-12-30)
      Article
      Accés obert
      We investigate the dynamics of cell signaling using an experimentally based Boolean model of the human fibroblast signal transduction network. We determine via systematic numerical simulations the relaxation dynamics of ...
    • Simulation methods with extended stability for stiff biochemical Kinetics 

      Rue Queralt, Pau; Villà-Freixa, Jordi; Burrage, Kevin (2010-08-11)
      Article
      Accés obert
      Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical systems involves a ...
    • The histone variant macroH2A is an epigenetic regulator of key developmental genes 

      Buschbeck, Markus; Uribesalgo, Iris; Wibowo, Indra; Rue Queralt, Pau; Martín, David; Gutiérrez, Arantxa; Morey, Lluís; Guigó, Roderic; López-Schier; Di Croce, Luciano (2009-09-06)
      Article
      Accés restringit per política de l'editorial
      The histone variants macroH2A1 1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the physiological function of macroH2A proteins on autosomes is poorly understood. Microarray-based ...