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Ara es mostren els items 95-114 de 125

    • Influence of gap junction dynamics on the stability of reentrant waves in cadiac tissue 

      Hawks, Claudia; Elorza Barbajero, Jorge; Echebarría Domínguez, Blas; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Bragard, Jean (2015)
      Text en actes de congrés
      Accés obert
      Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of ...

    • Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue 

      Hawks, Claudia; Elorza Barbajero, Jorge; Echebarría Domínguez, Blas; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Bragard, Jean (2016-01-01)
      Comunicació de congrés
      Accés obert
      Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of ...

    • Influence of the tubular network on the characteristics of calcium transients in cardiac myocytes 

      Marchena Angos, Miquel; Echebarría Domínguez, Blas (Public Library of Science (PLOS), 2020-04-17)
      Article
      Accés obert
      Transverse and axial tubules (TATS) are an essential ingredient of the excitation-contraction machinery that allow the effective coupling of L-type Calcium Channels (LCC) and ryanodine receptors (RyR2). They form a regular ...

    • Instability and spatiotemporal dynamics of alternans in paced cardiac tissue 

      Echebarría Domínguez, Blas; Karma, Alain (2002)
      Article
      Accés obert
      We derive an equation that governs the spatiotemporal dynamics of small amplitude alternans in paced cardiac tissue. We show that a pattern-forming linear instability leads to the spontaneous formation of stationary or ...

    • Mecánica. Problemas 1 

      Agea Tomás, José; Álvarez Casado, Enrique; Camí Babra, Enric; Castellví Gironès, Pedro Juan; Echebarría Domínguez, Blas; Formosa Mitjans, Joan; Peñaranda Ayllón, Angelina; Ramírez de la Piscina Millán, Laureano (Universitat Politècnica de Catalunya, 2009-09)
      Apunts / Problema, exercici
      Accés obert

    • Mecánica. Problemas 2 

      Agea Tomás, José; Álvarez Casado, Enrique; Camí Babra, Enric; Castellví Gironès, Pedro Juan; Echebarría Domínguez, Blas; Formosa Mitjans, Joan; Peñaranda Ayllón, Angelina; Ramírez de la Piscina Millán, Laureano (Universitat Politècnica de Catalunya, 2009-09)
      Apunts / Problema, exercici
      Accés obert

    • Mecánica. Problemas de examen 

      Agea Tomás, José; Auguet Sangrá, Carlota E.; Camí Babra, Enric; Castellví Gironès, Pedro Juan; Echebarría Domínguez, Blas; Lacasta Palacio, Ana María; Peñaranda Ayllón, Angelina; Ramírez de la Piscina Millán, Laureano; Rodríguez Cantalapiedra, Inma (Universitat Politècnica de Catalunya, 2010-09)
      Apunts / Problema, exercici
      Accés obert

    • Mechanisms for initiation of cardiac discordant alternans 

      Echebarría Domínguez, Blas; Karma, Alain (Springer, 2007-07-31)
      Article
      Accés restringit per política de l'editorial
      Electrical alternans, defined as a beat-to-beat change in the duration of the excited phase of cardiac cells, is among the known precursors of sudden cardiac death. It may appear as concordant (all the tissue presenting ...

    • Mechanisms Underlying Electro-Mechanical Cardiac Alternans 

      Echebarría Domínguez, Blas; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina (Springer, 2016-02-29)
      Capítol de llibre
      Accés restringit per política de l'editorial
      Electro-mechanical cardiac alternans consists in beat-to-beat changes in the strength of cardiac contraction. Despite its important role in cardiac arrhythmogenesis, its molecular origin is not well understood. The appearance ...

    • Minimal model for calcium alternans due to SR release refractoriness 

      Rodríguez Cantalapiedra, Inma; Álvarez Lacalle, Enrique; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas (Institute of Physics (IOP), 2017-09-07)
      Article
      Accés obert
      In the heart, rapid pacing rates may induce alternations in the strength of cardiac contraction, termed pulsus alternans. Often, this is due to an instability in the dynamics of the intracellular calcium concentration, ...

    • Modeling calcium dynamics in human atria 

      Rodríguez Cantalapiedra, Inma; Lugo Vélez, Carlos Antonio; Peñaranda Ayllón, Angelina; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2014-01-02)
      Article
      Accés restringit per política de l'editorial
      Mathematical models of cardiac electrophysiology are an important tool to investigate the underlying mecha- nisms responsible of arrhythmias. In particular, an im- portant question is the origin of atrial fibrillation ...

    • Modelización computacional cardiaca 

      Bragard, Jean; Camara Rey, Oscar; Echebarría Domínguez, Blas; Pueyo, Esther; Soudah Prieto, Eduardo; Vázquez, Mariano (Elsevier, 2020-08-01)
      Article
      Accés obert
      Las enfermedades cardiovasculares tienen en la actualidad un gran impacto social y económico y constituyen una de las principales causas de mortalidad y morbilidad. Los modelos computacionales personalizados del corazón ...

    • Multi-scale computational modeling of spatial calcium handling from nanodomain to whole-heart: overview and perspectives 

      Colman, Michael A.; Álvarez Lacalle, Enrique; Echebarría Domínguez, Blas; Sato, Daisuke; Sutanto, Henry; Heijman, Jordi (2022-03-09)
      Article
      Accés obert
      Regulation of intracellular calcium is a critical component of cardiac electrophysiology and excitation-contraction coupling. The calcium spark, the fundamental element of the intracellular calcium transient, is initiated ...

    • Nonlinear physics of electrical wave propagation in the heart: a review 

      Alonso Muñoz, Sergio; Baer, Markus; Echebarría Domínguez, Blas (2016-08-12)
      Article
      Accés obert
      The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over ...

    • Nonlinearities due to refractoriness in SR Ca release 

      Peñaranda Ayllón, Angelina; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Echebarría Domínguez, Blas (Institute of Electrical and Electronics Engineers (IEEE), 2013-01-01)
      Comunicació de congrés
      Accés obert
      Calcium alternans is a pro-arrhytmic cardiac dysfunction related to beat-to-beat changes in the amplitude of intracellular calcium transient, that typically occurs at rapid pacing rates. Although oscillations in sarcoplasmic ...

    • Nonlinearities due to refractoriness in SR Ca release 

      Peñaranda Ayllón, Angelina; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2012)
      Comunicació de congrés
      Accés obert
      Calcium alternans is a pro-arrhytmic cardiac dysfunction related to beat-to-beat changes in the amplitude of intracellular calcium transient, that typically occurs at rapid pacing rates. Although oscillations in sarcoplasmic ...

    • Onset of sidebranching in directional solidification 

      Echebarría Domínguez, Blas; Karma, Alain; Gurevich, Sebastian (2010-02-26)
      Article
      Accés obert
      We use a computationally efficient phase-field formulation [B. Echebarria et al., Phys. Rev. E 70, 061604 (2004)] to investigate the origin and dynamics of sidebranching in directional solidification for realistic ...

    • Phase-2 reentry in cardiac tissue: role of the slow calcium pulse 

      Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas; Bragard, Jean (2010-07-13)
      Article
      Accés obert
      Phase-2 re-entry is thought to underlie many causes of idiopathic ventricular arrhythmias as, for instance, those occurring in Brugada syndrome. In this paper, we study under which circumstances a region of depolarized tissue ...

    • Problemas 

      Agea Tomás, José; Álvarez Casado, Enrique; Auguet Sangrá, Carlota E.; Castellví Gironès, Pedro Juan; Alva, Aleix; Echebarría Domínguez, Blas; Lacasta Palacio, Ana María; Niubó Eslava, Maria; Peñaranda Ayllón, Angelina; Ramírez de la Piscina Millán, Laureano; Rodríguez Cantalapiedra, Inma; Camí Babra, Enric (Universitat Politècnica de Catalunya, 2010-09)
      Problema, exercici
      Accés obert

    • Propagation malfunctions due to gap junction dysregulation 

      Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas (2014)
      Comunicació de congrés
      Accés obert
      Gap junctions are membrane channels that connect the cytoplasm of adjacent cells allowing the cell-to-cell electrical coupling necessary for action potential propagation. Pathological conditions, such as malformations in ...