Exploració per autor "Benítez Iglesias, Raúl"
Ara es mostren els items 34-50 de 50
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Phase-field models in interfacial pattern formation out of equilibrium
(NOVA, 2004-06)
Capítol de llibre
Accés obert -
Phase-field study of transient stages and fluctuations in solidification
(Universitat Politècnica de Catalunya, 2005-01-27)
Tesi
Accés obertL'estudi de la formació de microstructures en processos de solidificació té importants aplicacions científiques i tecnològiques. L'aparició d'aquestes estructures determina les propietats elèctriques i mecàniques del ... -
Phospholamban knockout breaks arrhythmogenic Ca2+ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice
(2013-07-15)
Article
Accés restringit per política de l'editorialRationale: Phospholamban (PLN) is an inhibitor of cardiac sarco(endo)plasmic reticulum Ca2+ ATPase. PLN knockout (PLN-KO) enhances sarcoplasmic reticulum Ca2+ load and Ca2+ leak. Conversely, PLN-KO accelerates Ca2+ ... -
Pitx2c deficiency confers cellular electrophysiological hallmarks of atrial fibrillation to isolated atrial myocytes
(Elsevier, 2023-06-01)
Article
Accés obertAims Atrial fibrillation (AF) has been associated with altered expression of the transcription factor Pitx2c and a high incidence of calcium release-induced afterdepolarizations. However, the relationship between Pitx2c ... -
Prevention of adenosine A2A receptor activation diminishes beat-to-beat alternation in human atrial myocytes
(2016-01-01)
Article
Accés obert© 2015, Springer-Verlag Berlin Heidelberg. Atrial fibrillation (AF) has been associated with increased spontaneous calcium release from the sarcoplasmic reticulum and linked to increased adenosine A2A receptor (A2AR) ... -
Robust unsupervised detection of action potentials with probabilistic models
(Institute of Electrical and Electronics Engineers, 2008-04-30)
Article
Accés restringit per política de l'editorialWe develop a robust and fully unsupervised algorithm for the detection of action potentials from extracellularly recorded data. Using the continuous wavelet transform allied to probabilistic mixture models and Bayesian ... -
RyR2 serine-2030 PKA site governs Ca2+release termination and Ca2+alternans
(2023-01-20)
Article
Accés obertBackground: PKA (protein kinase A)–mediated phosphorylation of cardiac RyR2 (ryanodine receptor 2) has been extensively studied for decades, but the physiological significance of PKA phosphorylation of RyR2 remains ... -
Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP
(Elsevier, 2020-02-03)
Article
Accés obertFluorescent proteins are useful imaging and theranostic agents, but their potential superiority over alternative dyes is weakened by substantial photobleaching under irradiation. Enhancing protein photostability has been ... -
Semi-automatic GUI platform to characterize brain development in preterm children using ultrasound images
(2023-07-15)
Article
Accés obertThe third trimester of pregnancy is the most critical period for human brain development, during which significant changes occur in the morphology of the brain. The development of sulci and gyri allows for a considerable ... -
Spatial distribution of calcium sparks determines their ability to induce afterdepolarizations in human atrial myocytes
(Elsevier, 2023-01)
Article
Accés obertAnalysis of the spatio-temporal distribution of calcium sparks showed a preferential increase in sparks near the sarcolemma in atrial myocytes from patients with atrial fibrillation (AF), linked to higher ryanodine receptor ... -
Stochastic Phase-Field simulations of symmetric alloy solidification
(2004-09)
Article
Accés obertWe study initial transient stages in directional solidification by means of a non-variational phase field model with fluctuations. This model applies for the symmetric solidification of dilute binary solutions and does not ... -
The 4q25 variant rs13143308T links risk of atrial fibrillation to defective calcium homoeostasis
(2019-03-01)
Article
Accés obertAims: Single nucleotide polymorphisms on chromosome 4q25 have been associated with risk of atrial fibrillation (AF) but the exiguous knowledge of the mechanistic links between these risk variants and underlying ... -
The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2-ATPase, is a major determinant of Ca2 alternans in intact mouse hearts
(2018-07-09)
Article
Accés obertSarcoplasmic reticulum (SR) Ca2+ cycling is governed by the cardiac ryanodine receptor (RyR2) and SR Ca2+-ATPase (SERCA2a). Abnormal SR Ca2+ cycling is thought to be the primary cause of Ca2+ alternans that can elicit ... -
Translational diagnostics: an in-house pipeline to validate genetic variants in children with undiagnosed and rare diseases
(2021-01-13)
Article
Accés obertDiagnosis is essential for the management and treatment of patients with rare diseases. In a group of patients, the genetic study identifies variants of uncertain significance or inconsistent with the phenotype; therefore, ... -
TS-CNN: a three-tier self-interpretable CNN for multi-region medical image classification
(Institute of Electrical and Electronics Engineers (IEEE), 2023-07-31)
Article
Accés obertMedical image classification is critical, where reliability and transparency are crucial for the safe and accurate diagnosis of diseases. Deep Convolutional Neural Networks (DCNNs) are widely used in medical image ... -
ß2-adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co-activation of ryanodine receptor clusters
(2022-04-13)
Article
Accés obertAims It is unknown how ß-adrenergic stimulation affects calcium dynamics in individual RyR2 clusters and leads to the induction of spontaneous calcium waves. To address this, we analysed spontaneous calcium release ...
