Exploració per autor "Graffelman, Jan"
Ara es mostren els items 85-92 de 92
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On the testing of Hardy-Weinberg proportions and equality of allele frequencies in males and females at biallelic genetic markers
(2018-02-01)
Article
Accés obertStandard statistical tests for equality of allele frequencies in males and females and tests for Hardy-Weinberg equilibrium are tightly linked by their assumptions. Tests for equality of allele frequencies assume Hardy-Weinberg ... -
Some thoughts on counts in sequencing studies
(2020-12-01)
Article
Accés obertMeasurements in sequencing studies are mostly based on counts. There is a lack of theoretical developments for the analysis and modelling of this type of data. Some thoughts in this direction are presented, which might ... -
Statistical inference for Hardy-Weinberg equilibrium using log-ratio coordinates
(CIMNE, 2011)
Text en actes de congrés
Accés obertTesting markers for Hardy-Weinberg equilibrium (HWE) is an important step in the analysis of large databases used in genetic association studies. Gross deviation from HWE can be indicative of genotyping error. There are ... -
Statistical inference for Hardy-Weinberg proportions in the presence of missing genotype information
(2013-12-31)
Article
Accés obertIn genetic association studies, tests for Hardy-Weinberg proportions are often employed as a quality control checking procedure. Missing genotypes are typically discarded prior to testing. In this paper we show that ... -
Testing for Hardy–Weinberg equilibrium at biallelic genetic markers on the X chromosome
(2016-04-13)
Article
Accés obertTesting genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the ¿2 or exact test is applied ... -
The number of markers in the HapMap project: some notes on Chi-square and Exact tests for Hardy-Weinberg equilibrium
(2010-05-14)
Article
Accés restringit per política de l'editorial -
The transitivity of the Hardy-Weinberg law
(2022-05-01)
Article
Accés obertThe Hardy–Weinberg law is shown to be transitive in the sense that a multi-allelic polymorphism that is in equilibrium will retain its equilibrium status if any allele together with its corresponding genotypes is deleted ... -
Using compositional mixed-effects models to evaluate responses to amino acid supplementation in milk replacers for calves
(2021-07-01)
Article
Accés obertThe consequences of supplementing Lys, Met, and Thr in milk replacers (MR) for calves have been widely studied, but scarce information exists about potential roles of other AA (whether essential or not). The effects on ...
