Exploració per autor "Saperas Plana, Núria"
Ara es mostren els items 21-26 de 26
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Scaffolds for sustained release of ambroxol hydrochloride, a pharmacological Chaperone that Increases the Activity of Misfolded ß-Glucocerebrosidase
Enshaei, Hamidreza; Molina, Brenda G.; Valle Mendoza, Luis Javier del; Estrany Coda, Francesc; Arnan, Carme; Puiggalí Bellalta, Jordi; Saperas Plana, Núria; Alemán Llansó, Carlos (2019-01-01)
Article
Accés obertAmbroxol is a pharmacological chaperone (PC) for Gaucher disease that increases lysosomal activity of misfolded ß-glucocerebrosidase (GCase) while displaying a safe toxicological profile. In this work, different ... -
Sperm nuclear basic proteins and sperm chromatin organization in fish
Ausió, Juan; Saperas Plana, Núria; Chiva, Manel (World Aquaculture Society, 2011)
Capítol de llibre
Accés restringit per política de l'editorialSperm nuclear basic proteins (SNBPs) have been shown to consist of three main types: histone (H type), protamine-like (PL type) and protamine (P type). Fishes represent a unique group of vertebrates in that it includes ... -
Spermiogenesis and biflagellate spermatozoon of the teleost fish Lampanyctus crocodilus (Myctophiformes, Myctophidae): ultrastructure and characterisation of its sperm basic nuclear proteins
Ribes, Enric; Cheema, M; Gonzalez Romero, R.; LLORIS, D.; Ausió, Juan; Saperas Plana, Núria (2015-08-01)
Article
Accés obertWe undertook an ultrastructural study of the spermiogenesis of the lanternfish Lampanyctus crocodilus (Myctophiformes, Myctophidae) with special emphasis on the condensation of chromatin and the biochemical characterisation ... -
Sustained release of a pharmacological chaperone that increases the activity of misfolded ß-Glucocerebrosidase
Enshaei, Hamidreza; Molina García, Brenda Guadalupe; Valle Mendoza, Luis Javier del; Estrany Coda, Francesc; Arnan, Carme; Puiggalí Bellalta, Jordi; Saperas Plana, Núria; Alemán Llansó, Carlos (2019)
Comunicació de congrés
Accés obert -
The influence of Ni2+ and other ions on the trigonal structure of DNA
Acosta Reyes, Francisco Javier; Pagan, Mireia; Fonfría-Subirós, Elsa; Saperas Plana, Núria; Subirana Torrent, Juan A.; Campos López, Josefina de Lourdes (Wiley, 2021-04-13)
Article
Accés obertWe present a new structure of a DNA dodecamer obtained in the presence of Ni2+ ions. The DNA forms Ni-guanine cross-links between neighboring molecules. Our results show that an adequate dosage of Ni2+ may help to form ... -
Two high-mobility group box domains act together to underwind and kink DNA.
Sánchez Giraldo, Raquel; Acosta Reyes, Francisco Javier; Malarkey, Christopher S.; Saperas Plana, Núria; Churchill, Mair E. A.; Campos López, Josefina de Lourdes (2015-07-02)
Article
Accés obertHigh-mobility group protein 1 (HMGB1) is an essential and ubiquitous DNA architectural factor that influences a myriad of cellular processes. HMGB1 contains two DNA-binding domains, box A and box B, which have little ...