Ara es mostren els items 8-11 de 11

    • New drugs complexed with AT-rich DNA against neglected diseases 

      Millán, Cinthia; Acosta Reyes, Francisco Javier; Lagartera, Laura; Saperas Plana, Núria; Dardonville, Cristophe; De Koning, Harry Pieter; Campos López, Josefina de Lourdes (2019)
      Comunicació de congrés
      Accés restringit per política de l'editorial
    • Structure of the DNA duplex d(ATTAAT)(2) with Hoogsteen hydrogen bonds 

      Acosta Reyes, Francisco Javier; Subirana, Juan Antonio; Campos López, Josefina de Lourdes; Alechaga, Elida (2015-03-17)
      Article
      Accés obert
      The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is ...
    • The influence of Ni2+ and other ions on the trigonal structure of DNA 

      Acosta Reyes, Francisco Javier; Pagan, Mireia; Fonfría-Subirós, Elsa; Saperas Plana, Núria; Subirana Torrent, Juan A.; Campos López, Josefina de Lourdes (Wiley, 2021-04-13)
      Article
      Accés obert
      We present a new structure of a DNA dodecamer obtained in the presence of Ni2+ ions. The DNA forms Ni-guanine cross-links between neighboring molecules. Our results show that an adequate dosage of Ni2+ may help to form ...
    • Two high-mobility group box domains act together to underwind and kink DNA. 

      Sánchez Giraldo, Raquel; Acosta Reyes, Francisco Javier; Malarkey, Christopher S.; Saperas Plana, Núria; Churchill, Mair E. A.; Campos López, Josefina de Lourdes (2015-07-02)
      Article
      Accés obert
      High-mobility group protein 1 (HMGB1) is an essential and ubiquitous DNA architectural factor that influences a myriad of cellular processes. HMGB1 contains two DNA-binding domains, box A and box B, which have little ...