Exploració per autor "Pérez González, Juan Jesús"
Ara es mostren els items 48-57 de 57
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Social responsibility as a transversal competence of graduates
(2016)
Text en actes de congrés
Accés obertPaper purpose: The aim of the present communication is to propose a procedure to assess the level of competence achieved by graduates. Design/methodology/theoretical approach: We propose to use a quality assurance ... -
Structural characterization of a zinc high-affinity binding site in rhodopsin
(2009-02)
Article
Accés restringit per política de l'editorial -
Structural study of a new HIV-1 entry inhibitor and interaction with the HIV-1 fusion peptide in dodecylphosphocholine micelles
(2017-07-03)
Article
Accés obertPrevious studies support the hypothesis that the envelope GB virus C (GBV-C) E1 protein interferes the HIV-1 entry and that a peptide, derived from the region 139-156 of this protein, has been defined as a novel HIV-1 entry ... -
Structural study of a retro-enantiomer peptide with possible application in the pre-exposure prophylaxis of HIV infection
(Nature, 2020-09-02)
Article
Accés obertBased on the structure of an HIV-1 entry inhibitor peptide two stapled- and a retro-enantio peptides have been designed to provide novel prevention interventions against HIV transmission. The three peptides show greater ... -
Structure-activity studies of novel Di-substituted [1,2,5]oxadiazolo [3,4-b]pyrazine analogs targeting the A-loop regulatory site of p38 MAP kinase
(Bentham Science Publishers, 2022-03-01)
Article
Accés obertIntroduction: In the quest for novel allosteric inhibitors of the p38 MAP kinase, we recently described the A-loop regulatory site, identified by means of molecular modeling studies together with the disclosure of a small ... -
Synthesis, Langmuir and Langmuir-Blodgett films of a calix[7]arene ethyl ester
(Elsevier, 2012)
Article
Accés obert -
Synthesis, Langmuir and Langmuir-Blodgett films of a calix[7]arene ethyl ester. AFM characterization, subphase influence and molecular modelling
(Elsevier, 2012-05-05)
Article
Accés restringit per política de l'editorialCalixarenes are promising compounds to be used as ionophores and for molecular recognition. Their ability to form Langmuir and Langmuir–Blodgett (LB) films is of great interest in order to obtain small sensor devices which ... -
Topical application of an amygdalin analogue reduces inflammation and keratinocyte proliferation in a psoriasis mouse model
(2021-11-30)
Article
Accés obertPsoriasis is a chronic inflammatory skin disease without cure. Systemic and biological therapies are the most effective treatments for patients with severe psoriasis. However, these drugs can cause serious side effects ... -
Using molecular dynamics for the refinement of atomistic models of GPCRs by homology modeling
(2017-08-13)
Article
Accés obertDespite GPCRs sharing a common seven helix bundle, analysis of the diverse crystallographic structures available reveal specific features that might be relevant for ligand design. Despite the number of crystallographic ... -
Zinc is involved in depression by modulating G-protein-coupled receptor heterodimerization
(2016-04)
Article
Accés obert5-Hydroxytryptamine 1A receptor and galanin receptor 1 belong to the G protein-coupled receptors superfamily, and they have been described to heterodimerize triggering an anomalous physiological state that would underlie ...
