Ara es mostren els items 6-14 de 14

    • Hard epoxy thermosets obtained via two sequential epoxy-amine condensations 

      Konuray, Ali Osman; García, Aina; Morancho Llena, José María; Fernández Francos, Xavier; Serra Albet, Maria Àngels; Ferrando Piera, Francesc; García Álvarez, Montserrat; Ramis Juan, Xavier (Elsevier, 2019-07-01)
      Article
      Accés obert
      A new family of dual-curable poly(ß-hydroxyamine ether) thermosets based on amine-epoxy formulations has been prepared and characterized. Both curing stages consist in an epoxy-amine polycondensation, each having different ...
    • Hydrophobic modification of poly(gamma-glutamic acid) by grafting 4-phenyl-butyl side groups for the encapsulation and release of doxorubicin 

      Dorost, Porochista; García Álvarez, Montserrat; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon (Multidisciplinary Digital Publishing Institute (MDPI), 2023-05-16)
      Article
      Accés obert
      The delivery of drugs is a great challenge, since most of active pharmaceutical ingredients developed today are hydrophobic and poorly water soluble. From this perspective, drug encapsulation on biodegradable and biocompatible ...
    • Modification of microbial polymalic acid with hydrophobic amino acids for drug-releasing nanoparticles 

      Lanz, Alberto; García Álvarez, Montserrat; Portilla Arias, Jose Antonio; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Holler, Eggehard; Ljubimova, Julia Y.; Muñoz Guerra, Sebastián (2012-08-14)
      Article
      Accés restringit per política de l'editorial
      Microbial poly( β , L -malic acid) was modifi ed with either L -leucine ethyl ester (L) or L -phenylalanine methyl ester (F) to produce amphiphylic copolymers. The degradation of these copolymers in aqueous buffer took ...
    • Modification of microbial polymers by thiol-ene click reaction: Nanoparticle formation and drug encapsulation 

      Lanz, Alberto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; García Álvarez, Montserrat; Muñoz Guerra, Sebastián (2016-09-01)
      Article
      Accés obert
      Comb-like amphiphilic polymers were obtained by grafting long paraffinic chains on microbial poly(¿,dl-glutamic acid) and poly(ß,l-malic acid) through two steps, i.e. allylation of the carboxylic side groups followed by ...
    • Nanoparticles made of poly(gama-glutamic acid) derivatives for drug delivery systems 

      Dorost, Porochista; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; García Álvarez, Montserrat (2022)
      Comunicació de congrés
      Accés obert
      One of the treatments for cancer is chemotherapy but most anticancer drugs have a low therapeutic index, which causes toxicity complications in the healthy tissues [1]. To minimize these complications and improve the effect ...
    • Nanoparticles of esterified polymalic acid for controlled anticancer drug release 

      Lanz Landazuri, Alberto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Portilla Arias, Jose Antonio; García Álvarez, Montserrat; Holler, Eggehard; Ljubimova, Julia; Muñoz Guerra, Sebastián (2014-09-01)
      Article
      Accés restringit per política de l'editorial
      Esterification of microbial poly(malic acid) is performed with either ethanol or 1-butanol to obtain polymalate conjugates capable to form nanoparticles (100–350 nm). Degradation under physiological conditions takes place ...
    • Poly(methyl malate) nanoparticles: formation, degradation, and encapsulation of anticancer drugs 

      Lanz, Alberto; García Álvarez, Montserrat; Portilla Arias, Jose Antonio; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Patil, Rameshwar; Holler, Eggehard; Ljubimova, Julia Y.; Muñoz Guerra, Sebastián (2011-10-10)
      Article
      Accés restringit per política de l'editorial
      PMLA nanoparticles with diameters of 150–250nm are prepared, and their hydrolytic degradation is studied under physiological conditions. Degradation occurs by hydrolysis of the side chain methyl ester followed by cleavage ...
    • Poly(ß,L-malic acid)/Doxorubicin ionic complex: A pH-dependent delivery system 

      Lanz Landazuri, Alberto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; García Álvarez, Montserrat; Muñoz Guerra, Sebastián (2014-08-01)
      Article
      Accés restringit per política de l'editorial
      Poly(beta,L-malic acid) (PMLA) was made to interact with the cationic anticancer drug Doxorubicin (DOX) in aqueous solution to form ionic complexes with different compositions and an efficiency near to 100%. The PMLA/DOX ...
    • Time-temperature-transformation (TTT) diagram of dual-curable epoxy thermosets obtained via two sequential epoxy-amine condensations 

      Konuray, Ali Osman; Salla Tarragó, José María; Morancho Llena, José María; Fernández Francos, Xavier; García Álvarez, Montserrat; Ramis Juan, Xavier (2019-08-01)
      Article
      Accés obert
      A simple and robust strategy to generate time-temperature-transformation (TTT) diagrams for dual-curable thermosets is presented. TTT diagram is built for a dual-curable amine-epoxy formulation. Both curing stages are ...