Exploració per autor "Garriga Solé, Pere"
Ara es mostren els items 13-32 de 44
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Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
Razzaghi, Neda; Fernández González, Pol; Mas Sánchez, Aina; Vila i Julià, Guillem; Pérez González, Juan Jesús; Garriga Solé, Pere (2021-05-19)
Article
Accés obertRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Effect of trace metal Ions on the conformational stability of the visual photoreceptor rhodopsin
Wang, Feifei; Fernández González, Pol; Ramon Portés, Eva; Gómez Gutiérrez, Patricia; Morillo Cazorla, Margarita; Garriga Solé, Pere (Multidisciplinary Digital Publishing Institute (MDPI), 2023-07-01)
Article
Accés obertTrace metals are essential elements that play key roles in a number of biochemical processes governing human visual physiology in health and disease. Several trace metals, such as zinc, have been shown to play important ... -
Estructura tridimensional de la rodopsina
Valle Mendoza, Luis Javier del; Garriga Solé, Pere; Götzens García, Guadalupe; Urtubia Vicario, César; Ramon Portés, Eva; Gómez, Jesús (PUNTEX, 2002-06)
Article
Accés obertLa rodopsina es un fotopigmento localizado en las membranas discoidales de los fotorreceptores de la retina de los vertebrados que desempeña una función central en el complejo fenómeno de la visión. Determinadas alteraciones ... -
Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa
Herrera Hernández, María Guadalupe; Ramon Portés, Eva; Lupala, Cecylia Severin; Tena Campos, Mercè; Pérez González, Juan Jesús; Garriga Solé, Pere (Macmillan Publishers, 2017-12-01)
Article
Accés obertDietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural ... -
Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution
Fernandez-Sampedro, Miguel angel; Invergo, Brandon M.; Ramon Portés, Eva; Bertranpetit, Jaume; Garriga Solé, Pere (Macmillan Publishers, 2016-02-11)
Article
Accés obertVisual rhodopsins are membrane proteins that function as light photoreceptors in the vertebrate retina. Specific amino acids have been positively selected in visual pigments during mammal evolution, which, as products of ... -
G protein-coupled receptor heterodimerization in the brain
Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garriga Solé, Pere; Ciruela, Francisco; Narvaez, Manuel; Tarakanov, O.V.; Palkovits, Miklós; Agnati, Luigi F.; Fuxe, Kjell (2013)
Article
Accés restringit per política de l'editorialG protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and have been shown to form heteromers with diverge biochemical and/or pharmacological activities that are different from those ... -
Hsp90 inhibition protects against inherited retinal degeneration
Aguilà, Mònica; Bevilacqua, Dalila; McCulley, Caroline; Schwarz, Nele; Athanasiou, Dimitra; Kanuga, Naheed; Novoselov, Sergey S.; Lange, Clemens A.K.; Ali, Robin R.; Bainbridge, James W.; Gias, Carlos; Coffey, Peter J.; Garriga Solé, Pere; Cheetham, Michael E. (2014-04-15)
Article
Accés obertThe molecular chaperone Hsp90 is important for the functional maturation of many client proteins, and inhibitors are in clinical trials for multiple indications in cancer. Hsp90 inhibition activates the heat shock response ... -
Human blue cone opsin regeneration involves secondary retinal binding with analog specificity
Srinivasan, Sundaramoorthy; Fernández Sampedro, Miguel Ángel; Morillo Cazorla, Margarita; Ramon Portés, Eva; Jiménez Rosés, Mireia; Cordomi, Arnau; Garriga Solé, Pere (2018-03-27)
Article
Accés obertHuman color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual ... -
Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation
Bosch Presegué, Laia; Iarriccio Silva, Laura; Aguila Cerda, Mónica; Toledo, Darwin; Ramon Portés, Eva; Cordomí Montoya, Arnau; Garriga Solé, Pere (2011-02-15)
Article
Accés restringit per política de l'editorialRhodopsin is the visual photoreceptor responsible for dim light vision. This receptor is located in the rod cell of the retina and is a prototypical member of the G-protein-coupled receptor superfamily. The structural ... -
Informe científico del proyecto "Modificación del plegamiento y función de opsinas mutadas mediante factores celulares como nueva estrategia terapéutica para enfermedades degenerativas de la retina"
Garriga Solé, Pere (2016-05-18)
Report de recerca
Accés obertLas mutaciones en la rodopsina son la principal causa de retinosis pigmentaria (RP) autosómica dominante. Estas mutaciones pueden clasificarse según sus propiedades bioquímicas y celulares. Por ejemplo las de tipo II son ... -
Ligand binding mechanisms in human cone visual pigments
Srinivasan, Sundaramoorthy; Guixà González, Ramon; Cordomí, Arnau; Garriga Solé, Pere (2019-07)
Article
Accés obertVertebrate vision starts with light absorption by visual pigments in rod and cone photoreceptor cells of the retina. Rhodopsin, in rod cells, responds to dim light, whereas three types of cone opsins (red, green, and blue) ... -
MATERIALS ÒPTICS (Examen 1r quadrimestre, 2n parcial)
Garriga Solé, Pere (Universitat Politècnica de Catalunya, 2017-01-20)
Examen
Accés restringit a la comunitat UPC -
MATERIALS ÒPTICS (Examen 1r quadrimestre, 2n parcial)
Garriga Solé, Pere (Universitat Politècnica de Catalunya, 2018-01-11)
Examen
Accés restringit a la comunitat UPC -
MATERIALS ÒPTICS (Examen 2n quadrimestre, 2n parcial)
Garriga Solé, Pere (Universitat Politècnica de Catalunya, 2019-06-06)
Examen
Accés restringit a la comunitat UPC -
Mecanisme per a inserir passadors en un dissipador de calor
Garriga Solé, Pere (Universitat Politècnica de Catalunya, 2011-01-12)
Projecte/Treball Final de Carrera
Accés obertActualment existeix una empresa que en el desenvolupament de la seva activitat industrial elabora unes peces d’alumini que tenen la funció de dissipar el calor en els transistors, plaques de circuit imprès, fonts d’alimentació ... -
Mecanismo de activación de la rodopsina: unión y activación de la proteína-G transducina
Valle Mendoza, Luis Javier del; Garriga Solé, Pere; Bosch Presegué, Laia; Ramon Portés, Eva; Götzens García, Guadalupe; Urtubia Vicario, César (PUNTEX, 2002-11)
Article
Accés obertLa rodopsina es la proteína fotorreceptora de la retina que pertenece a la superfamilia de receptores acoplados a proteína G (GPRC). Ésta es una de las familias de proteínas transductoras de señal más amplia y de gran ... -
Mercury-induced dark-state instability and photobleaching alterations of the visual G-protein coupled receptor rhodopsin
Morillo Cazorla, Margarita; Toledo Gonzalez, Darwin; Pérez González, Juan Jesús; Ramon Portés, Eva; Garriga Solé, Pere (2014-07-01)
Article
Accés restringit per política de l'editorialMercuric compounds were previously shown to affect the visual phototransduction cascade, and this could result in vision impairment. We have analyzed the effect of mercuric chloride on the structure and stability of the ... -
Molecular mechanisms of retinal toxicity induced by light and chemical damage
Herrera Hernández, María Guadalupe; Ramon Portés, Eva; Garriga Solé, Pere (Elsevier, 2015-10-11)
Capítol de llibre
Accés restringit per política de l'editorialIn recent years, important advances have been made to decipher the multiple defense mechanisms of the retina (a highly specialized sense tissue) against several extreme conditions, such as constant exposure to systemic ... -
New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations
Herrera Hernández, María Guadalupe; Razzaghi, Neda; Fernández González, Pol; Bosch Presegue, Laia; Vila i Julià, Guillem; Pérez González, Juan Jesús; Garriga Solé, Pere (Springer Nature, 2022-01-01)
Article
Accés obertMutations in the photoreceptor protein rhodopsin are known as one of the leading causes of retinal degeneration in humans. Two rhodopsin mutations, Y102H and I307N, obtained in chemically mutagenized mice, are currently ... -
Novel ligands for the treatment of retinal degenerative diseases
Wang, Feifei; Fernández González, Pol; Morillo Cazorla, Margarita; Garriga Solé, Pere (2023-05-17)
Comunicació de congrés
Accés obert