Exploració per autor "Mothe, Beatriz"

Ara es mostren els items 1-4 de 4

    • Definition of the viral targets of protective HIV-1-specific T cell responses 

      Pérez-Alvarez, Susana; Mothe, Beatriz; Llano, Anuska; Ibarrondo, Javier; Daniels, Marcus; Miranda, Cristina; Zamarreño, Jennifer; Bach, Vanessa; Zuniga, Rosario; Brander, C.; Sanchez, Jorge; Brumme, Chanson J.; Sánchez-Merino, Victor; Yang, Otto O.; Hildebrand, William H.; Szinger, James J.; Farfan, Marilu; Rolland, Morgane; Martínez-Picado, Javier; Puertas, Maria C.; Berger, Chistoph T.; Brumme, Zabrina L.; Korber, Bette T.; Gatell, Jose M.; Clotet, Bonaventura; Goulder, Philip J.; Walker, Bruce D.; Mullins, James I.; Gómez Melis, Guadalupe; Heckerman, David; Allen, Todd M. (2011-12-07)
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      Background: The efficacy of the CTL component of a future HIV-1 vaccine will depend on the induction of responses with the most potent antiviral activity and broad HLA class I restriction. However, current HIV vaccine ...

    • Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection 

      Prats París, Anna; Martínez Zalacaín, Ignacio; Mothe, Beatriz; Negredo Puigmal, Eugènia; Pérez Álvarez, Nuria; Garolera, Maite; Domènech Puigcerver, Sira; Coll, Pep; Meulbroek, M.; Chamorro, Anna; Rodriguez Fumaz, Carmina; Ferrer, Maria; Clotet Sala, Bonaventura; Soriano Mas, Carles; Muñoz Moreno, Jose Antonio (Nature, 2021-12-01)
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      Accés obert
      Integrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral regimens recommended for treatment of HIV infection. However, little is known about the impact of INSTI on neurocognition and ...

    • HIVconsv vaccines and romidepsin in early-treated HIV-1-infected individuals: safety, immunogenicity and effect on the viral reservoir (Study BCN02) 

      Mothe, Beatriz; Rosas Umbert, Miriam; Coll, Pep; Manzardo, Christian; Puertas Castro, Maria C.; Morón López, Sara; Llano, Anuska; Alarcón Soto, Yovaninna; Gómez Melis, Guadalupe; Langohr, Klaus (2020-05-06)
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      Kick&kill strategies combining drugs aiming to reactivate the viral reservoir with therapeutic vaccines to induce effective cytotoxic immune responses hold potential to achieve a functional cure for HIV-1 infection. Here, ...

    • Identification of interleukin-27 (IL-27)/IL-27 receptor subunit alpha as a critical immune axis for in vivo hiv control 

      Ruiz-Riol, M.; Berdnik, D.; Llano, A.; Mothe, Beatriz; Gálvez, C.; Pérez Álvarez, Susana; Oriol Tordera, B.; Olvera Van der Stoep, Alex; Silva Arrieta, S.; Meulbroek, M.; Salvat Pujol, Francesc; Coll, J.; Martínez Picado, Javier; Ganoza, Carmela; Sánchez, J.; Gómez Melis, Guadalupe; Coray, Wyss; Brander, Christian (2017-08-01)
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      Accés obert
      Intact and broad immune cell effector functions and specific individual cytokines have been linked to HIV disease outcome, but their relative contribution to HIV control remains unclear. We asked whether the proteome of ...