Exploració per autor "Manzo, Carlo"
Ara es mostren els items 1-8 de 8
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DNA Origami offers a versatile method for quantifying protein copy‐number in superresolution
Zanacchi, Francesca Cella; Manzo, Carlo; Sandoval Alvarez, Angel; Derr, Nathan D.; Garcia-Parajo, Maria F.; Lakadamyali, Melike (Nature, 2017-06-26)
Article
Accés obertSingle-molecule-based super-resolution microscopy offers researchers a unique opportunity to quantify protein copy number with nanoscale resolution. However, while fluorescent proteins have been characterized for quantitative ... -
Planar Optical Nanoantennas Resolve Cholesterol-Dependent Nanoscale Heterogeneities in the Plasma Membrane of Living Cells
Regmi, Raju; Winkler, Pamina M.; Flauraud, Valentin; Borgman, Kyra J. E.; Manzo, Carlo; Brugger, Jürgen; Rigneault, Hervé; Wenger, Jérôme; Garcia-Parajo, Maria F. (ACS, 2017-09-19)
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Accés obertOptical nanoantennas can efficiently confine light into nanoscopic hotspots, enabling single-molecule detection sensitivity at biological relevant conditions. This innovative approach to breach the diffraction limit offers ... -
PLANT: A Method for Detecting Changes of Slope in Noisy Trajectories
Sosa-Costa, Alberto; Piechocka, Izabela K.; Gardini, Lucia; Pavone, Francesco S.; Capitanio, Marco; Garcia-Parajo, Maria F.; Manzo, Carlo (ScienceDirect, 2018-05-08)
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Accés obertTime traces obtained from a variety of biophysical experiments contain valuable information on underlying processes occurring at the molecular level. Accurate quantification of these data can help explain the details of ... -
Priming by Chemokines Restricts Lateral Mobility of the Adhesion Receptor LFA-1 and Restores Adhesion to ICAM-1 Nano-Aggregates on Human Mature Dendritic Cells
Borgman, Kyra J.; Zanten, Thomas S. van; Manzo, Carlo; Cabezón, Raquel; Cambi, Alessandra; Benítez-Ribas, Daniel; Garcia-Parajo, Maria F. (PLOS, 2014-06-19)
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Accés obertLFA-1 is a leukocyte specific β2 integrin that plays a major role in regulating adhesion and migration of different immune cells. Recent data suggest that LFA-1 on mature dendritic cells (mDCs) may function as a ... -
Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T cell migration
Piechocka, Izabela K.; Keary, Sarah; Sosa-Costa, Alberto; Lau, Lukas; Mohan, Nitin; Stanisavljevic, Jelena; Borgman, Kyra J.E.; Lakadamyali, Melike; Manzo, Carlo; Garcia-Parajo, Maria F. (Biophysical Society, 2021-06-01)
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Accés obertThe leukocyte specific β2-integrin LFA-1, and its ligand ICAM-1 expressed on endothelial cells (ECs), are involved in the arrest, adhesion and transendothelial migration of leukocytes. Although the role of mechanical ... -
Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration
Piechocka, Izabela K.; Keary, Sarah; Sosa-Costa, Alberto; Lau, Lukas; Mohan, Nitin; Stanisvljevic, Jelena; Borgman, Kyra; Lakadamyali, Melike; Manzo, Carlo; Garcia-Parajo, Maria F. (2021-06)
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Accés obertThe leukocyte-specific ß2-integrin LFA-1 and its ligand ICAM-1, expressed on endothelial cells (ECs), are involved in the arrest, adhesion, and transendothelial migration of leukocytes. Although the role of mechanical ... -
The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells*
Manzo, Carlo; Torreño Piña, Juan Andrés; Joosten, Ben; Reinieren Beeren, Inge; Gualda Manzano, Emilio José; Loza Álvarez, Pablo; Figdor, Carl G.; Garcia-Parajo, Maria F.; Cambi, Alessandra (2012-11)
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Accés obertThe C-type lectin DC-SIGN expressed on dendritic cells(DCs) facilitates capture and internalization of a plethora of dif-ferent pathogens. Although it is known that DC-SIGN organizesin nanoclusters at the surface of DCs, ... -
Weak Ergodicity Breaking of Receptor Motion in Living Cells Stemming from Random Diffusivity
Manzo, Carlo; Torreno-Pina, Juan A.; Massignan, Pietro; Lapeyre, Gerald J.; Lewenstein, Maciej; Garcia-Parajo, Maria F. (APS Physics, 2015-02-25)
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Accés obertMolecular transport in living systems regulates numerous processes underlying biological function. Although many cellular components exhibit anomalous diffusion, only recently has the subdiffusive motion been associated ...