Exploració per tema "Proteomics"
Ara es mostren els items 1-17 de 17
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A deep learning-based method for uncovering GPCR ligand-induced conformational states using interpretability techniques
(Springer, 2022)
Text en actes de congrés
Accés obertThere is increasing interest in the development of tools for investigating the protein ligand space. Understanding the underlying mechanisms of G protein-coupled receptors (GPCR) in the ligand-binding process is of particular ... -
A model of large-scale proteome evolution
(2002-03)
Article
Accés obertThe next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent ... -
An application of Dynamic Programming to Spectra Coding for PIPI
(Universitat Politècnica de Catalunya, 2020-05-21)
Treball Final de Grau
Accés obert
Realitzat a/amb: Hong Kong University of Science and TechnologyPIPI és un software per identificar péptids amb un nombre il·limitat de modificacions post-traducció (PTM). La identificació resulta intratable si es volen considerar tots els tipus posibles de PTM. La codificació dels ... -
Analysis of incomplete gene expression dataset through protein-protein interaction information
(2011)
Text en actes de congrés
Accés restringit per política de l'editorialThis paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties ... -
Complex networks in genomics and proteomics
(Wiley-VCH, 2003)
Capítol de llibre
Accés restringit per política de l'editorialComplex interacting networks are observed in systems from such diverse areas as physics, biology, economics, ecology, and computer science. For example, economic or social interactions often organize themselves in complex ... -
Development of a protein quantification algorithm for data analysis in the field of proteomics
(Universitat Politècnica de Catalunya, 2014-01-22)
Projecte/Treball Final de Carrera
Accés obert
Realitzat a/amb: University of WashingtonDesenvolupament d'un algorisme de quantificació proteòmica i d'un mòdul web per a la seva utilització. L'objectiu de la quantificació proteòmica és obtenir informació quantitativa sobre els pèptids que es troben en una ... -
Development of a web interface for managing scientific applications in the field of proteomics
(Universitat Politècnica de Catalunya, 2014-11-01)
Treball Final de Grau
Accés restringit per acord de confidencialitat
Realitzat a/amb: University of Washington -
Evolving protein interaction networks through gene duplication
(2003-05-21)
Article
Accés obertThe topology of the proteome map revealed by recent large-scale hybridization methods has shown that the distribution of protein–protein interactions is highly heterogeneous, with many proteins having few edges while a few ... -
Exploratory visualization of misclassified GPCRs from their transformed unaligned sequences using manifold learning techniques
(Copicentro Granada, 2014)
Text en actes de congrés
Accés obertClass C G-protein-coupled receptors (GPCRs) are cell membrane proteins of great relevance to biology and pharmacology. Previous research has revealed an upper boundary on the accuracy that can be achieved in their ... -
Finding class C GPCR subtype-discriminating n-grams through feature selection
(Springer International Publishing, 2014)
Text en actes de congrés
Accés obertG protein-coupled receptors (GPCRs) are a large and heterogeneous superfamily of receptors that are key cell players for their role as extracellular signal transmitters. Class C GPCRs, in particular, are of great interest ... -
Label noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors
(2015-09-29)
Article
Accés obertBackground: The characterization of proteins in families and subfamilies, at different levels, entails the definition and use of class labels. When the adscription of a protein to a family is uncertain, or even wrong, this ... -
Layer-wise relevance analysis for motif recognition in the activation pathway of the ß2-adrenergic GPCR receptor
(2023-01-06)
Article
Accés obertG-protein-coupled receptors (GPCRs) are cell membrane proteins of relevance as therapeutic targets, and are associated to the development of treatments for illnesses such as diabetes, Alzheimer’s, or even cancer. Therefore, ... -
Misclassification of class C G-protein-coupled receptors as a label noise problem
(2014)
Comunicació de congrés
Accés obertG-Protein-Coupled Receptors (GPCRs) are cell membrane proteins of relevance to biology and pharmacology. Their supervised classification in subtypes is hampered by label noise, which stems from a combination of expert ... -
Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources
(Public Library of Science (PLOS), 2022-03)
Article
Accés obertMany fungal species utilize hydroxyderivatives of benzene and benzoic acid as carbon sources. The yeast Candida parapsilosis metabolizes these compounds via the 3-oxoadipate and gentisate pathways, whose components are ... -
Use of Gene Ontology semantic information in protein interaction data visualization
(IEEE Press. Institute of Electrical and Electronics Engineers, 2008)
Text en actes de congrés
Accés obertThe Gene Ontology project is an effort to structure knowledge on biological products and processes by adding semantic information to them. This is done in a systematic way so that this additional information can be ... -
Using machine learning tools for protein database biocuration assistance
(Nature, 2018-07-05)
Article
Accés obertBiocuration in the omics sciences has become paramount, as research in these fields rapidly evolves towards increasingly data-dependent models. As a result, the management of web-accessible publicly-available databases ... -
Visual interpretation of class C GPCR subtype overlapping from the nonlinear mapping of transformed primary sequences
(Institute of Electrical and Electronics Engineers (IEEE), 2014)
Text en actes de congrés
Accés restringit per política de l'editorialThis brief paper addresses the problem of visually assessing the natural discriminability of the different subtypes that characterize class C G-Protein-Coupled Receptors, which are membrane proteins of interest in pharmacology, ...