• Efectes de compostos naturals en els receptors visuals 

      Stolarczyk Okarma, Verònica (Universitat Politècnica de Catalunya, 2023-07-28)
      Projecte Final de Màster Oficial
      Accés obert
      Objectiu Aquest treball se centra en estudiar l’efecte dels compostos naturals en l’estabilitat i capacitat de regenerar la rodopsina que presenta mutacions associades a la retinosi pigmentària(RP). Els compostos naturals ...
    • Exploratory analysis of the molecular dynamics of cannabinoid receptor proteins 

      Rubio Cuervo, Damián (Universitat Politècnica de Catalunya, 2020-10)
      Projecte Final de Màster Oficial
      Accés obert
      G protein-coupled receptors, also known as GPCRs, are a kind of protein receptors that transfer signals to the inner part of cells when a certain kind of molecule is detected outside. In this thesis this kind of receptors ...
    • G protein-coupled receptor heterodimerization in the brain 

      Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garriga Solé, Pere; Ciruela, Francisco; Narvaez, Manuel; Tarakanov, O.V.; Palkovits, Miklós; Agnati, Luigi F.; Fuxe, Kjell (2013)
      Article
      Accés restringit per política de l'editorial
      G protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and have been shown to form heteromers with diverge biochemical and/or pharmacological activities that are different from those ...
    • Obtención de receptores muscarínicos de acetilcolina recombinantes involucrados en patologías neurodegenerativas 

      Martínez Sánchez, Luz del Carmen (Universitat Politècnica de Catalunya, 2014-02)
      Projecte Final de Màster Oficial
      Accés obert
      Recientemente se han logrado grandes avances en la determinación de la estructura y función de los receptores acoplados a proteínas G (GPCR’s). Los GPCR´s constituyen gran familia de proteína integrales de membrana y se ...
    • Skin tastes bitter molecules through the bitter taste receptors 

      Roca, Angela; Perez Aso, Miguel; Tena Campos, Mercè; Garriga Solé, Pere; Bosch, Jordi; Martinez Teipel, Blanca (2018)
      Comunicació de congrés
      Accés restringit per política de l'editorial
    • Uncovering non-ergodicity on the cell membrane using single particle tracking approaches 

      Symeonidou Besi, Parthena (Universitat Politècnica de Catalunya, 2013-09-05)
      Projecte Final de Màster Oficial
      Accés obert
      [ANGLES] In this work, we study the diffusion on the plasma membrane of the receptor DC-SIGN. The data we used were obtained by Single Particle Tracking technique and hence consist of individual trajectories. Motivated by ...
    • Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs 

      Pontes, Camila; Ruiz Serra, Victoria; Lepore, Rosalba; Valencia, Alfonso (Elsevier, 2021)
      Article
      Accés obert
      The recent emergence of the novel SARS-CoV-2 in China and its rapid spread in the human population has led to a public health crisis worldwide. Like in SARS-CoV, horseshoe bats currently represent the most likely candidate ...
    • Zinc is involved in depression by modulating G-protein-coupled receptor heterodimerization 

      Tena Campos, Mercè; Ramon Portés, Eva; Lupala, Cecylia Severin; Pérez González, Juan Jesús; Koch, Karl-Wilhelm; Garriga Solé, Pere (2016-04)
      Article
      Accés obert
      5-Hydroxytryptamine 1A receptor and galanin receptor 1 belong to the G protein-coupled receptors superfamily, and they have been described to heterodimerize triggering an anomalous physiological state that would underlie ...