Ara es mostren els items 1-20 de 44

    • A FM-index transformation to enable large k-steps 

      Langarita, Rubén; Armejach Sanosa, Adrià; Moretó Planas, Miquel (Barcelona Supercomputing Center, 2019-05-07)
      Text en actes de congrés
      Accés obert
    • A multilayer network approach to elucidate severity in Congenital Myasthenic Syndromes 

      Núñez-Carpintero, Iker; Cirillo, Davide; Valencia, Alfonso (Barcelona Supercomputing Center, 2019-05-07)
      Text en actes de congrés
      Accés obert
    • Binding and orientation of 3D DNA structures on UV-lithography patterned PIII surface 

      Taulé Flores, Pere (Universitat Politècnica de Catalunya, 2018-02-07)
      Treball Final de Grau
      Accés obert
      Realitzat a/amb:   University of Sydney
      DNA nanotechnology shows promising applications due to its ability to present more than 200 functionizable sites on its structure with a 6nm spatial resolution. However, DNA nanostructures cannot be directly self-assembled ...
    • Biochemical noise in single DNA molecule studied by optical trapping technique 

      Martínez Sánchez, Ignacio A. (Universitat Politècnica de Catalunya, 2010-09-09)
      Projecte Final de Màster Oficial
      Accés obert
      Noise spectra from single DNA molecules in their natural aqueous environment at different grades of stretching are presented. A DNA molecule is anchored between two dielectric beads. One of the beads is fixed to the surface ...
    • Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus 

      Colabardini, Ana Cristina; Wang, Fang; Miao, Zhengqiang; Pardeshi, Lakhansing; Valero, Clara; Marcet Houben, Marina; Gabaldón, Toni (Public Library of Science, 2022-01)
      Article
      Accés obert
      Invasive Pulmonary Aspergillosis, which is caused by the filamentous fungus Aspergillus fumigatus, is a life-threatening infection for immunosuppressed patients. Chromatin structure regulation is important for genome ...
    • Cis and trans effects differentially contribute to the evolution of promoters and enhancers 

      Mattioli, Kaia; Oliveros, Winona; Gerhardinger, Chiara; Andergassen, Daniel; Maass, Philipp G.; Rinn, John L.; Melé, Marta (Springer Nature, 2020-08-20)
      Article
      Accés obert
      Background Gene expression differences between species are driven by both cis and trans effects. Whereas cis effects are caused by genetic variants located on the same DNA molecule as the target gene, trans effects are ...
    • Controllability of a magnetic cell stretching device 

      Domingo Oriol, Antonio (Universitat Politècnica de Catalunya, 2018-06-24)
      Treball Final de Grau
      Accés obert
      The control of coordinated gene expression is one of the most important processes due to its importance in understanding diseases caused by genomic problems. For it, it is important to study the role of genomic DNA ...
    • Critical analysis and comparison of data protection techniques for genomics data sets 

      Naro, Daniel (Universitat Politècnica de Catalunya, 2016-07-04)
      Projecte Final de Màster Oficial
      Accés obert
      This work reviews the current literature on protecting genomic information. The goal is to provide insight on how to define a secure file format for such data. We compare the published ideas to the requirements defined by ...
    • Crystal structure of a complex of DNA with one AT-hook of HMGA1 

      Fonfria Subirós, Elsa; Acosta Reyes, Francisco Javier; Saperas Plana, Núria; Pous, Joan; Subirana Torrent, Juan A.; Campos López, Josefina de Lourdes (2012-05-16)
      Article
      Accés obert
      We present here for the first time the crystal structure of an AT-hook domain. We show the structure of an AT-hook of the ubiquitous nuclear protein HMGA1, combined with the oligonucleotide d(CGAATTAATTCG)2, which has two ...
    • Design Tools for Reinforced 3D DNA Nanostructures 

      Corcoll Andreu, Oriol (Universitat Politècnica de Catalunya, 2014-06-17)
      Treball Final de Grau
      Accés obert
      In this document we present an algorithm which takes a structure and a path for the scaffold as input and reinforces its long edges with a bipyramid-like structure. Also we give a tool to visualise the original structure, ...
    • Detection of transcription factor binding sites using Rényi entropy 

      Maynou Fernández, Joan; Vallverdú Ferrer, Montserrat; Clarià, Francesc; Perera Lluna, Alexandre; Caminal Magrans, Pere (IEEE Press. Institute of Electrical and Electronics Engineers, 2008)
      Text en actes de congrés
      Accés obert
      During the process of protein synthesis, transcription of DNA to messenger RNA starts with the binding of the transcription factors to the promoter. One of the issues on the prediction of transcription factor binding is ...
    • DNA - Conducting polymer complexes: A computational study of the hydrogen bond between building blocks 

      Zanuy Gomara, David; Alemán Llansó, Carlos (2012)
      Article
      Accés obert
      Ab initio quantum mechanical calculations at the MP2 level were used for an extensive study concerning the stability of hydrogen-bonded complexes formed by pyrrole and thiophene, which are the most common building blocks ...
    • DNA adsorbed on hydroxyapatite surfaces 

      Valle Mendoza, Luis Javier del; Bertran Cànovas, Òscar; Chaves Barboza, Gustavo Adolfo; Revilla López, Guillermo; Rivas Cañas, Manuel; Casanovas Muñoz, Jordi; Turón Dols, Pau; Puiggalí Bellalta, Jordi; Alemán Llansó, Carlos; Casas, Maria Teresa (Royal Society of Chemistry, 2014-01-01)
      Article
      Accés obert
      Hydroxyapatite (HAp) particles with very different surface charges and compositions (i.e. different Ca/P and CO32-/PO43- ratios) have been obtained by varying the experimental conditions used during the chemical precipitation ...
    • DNA deposition through laser induced forward transfer 

      Colina Brito, Mónica Alejandra; Serra Coromina, Pere; Fernández Pradas, J. Marcos; Sevilla, Lidia; Morenza, José L. (2004-10-22)
      Article
      Accés restringit per política de l'editorial
      Laser direct writing; LIFT; DNA; Microarrays
    • DNA Origami offers a versatile method for quantifying protein copy‐number in superresolution 

      Zanacchi, Francesca Cella; Manzo, Carlo; Sandoval Alvarez, Angel; Derr, Nathan D.; Garcia-Parajo, Maria F.; Lakadamyali, Melike (Nature, 2017-06-26)
      Article
      Accés obert
      Single-molecule-based super-resolution microscopy offers researchers a unique opportunity to quantify protein copy number with nanoscale resolution. However, while fluorescent proteins have been characterized for quantitative ...
    • DNA tracking within a nanochannel: device fabrication and experiments 

      Mokkapati, V. R. S. S.; Virgilio, Vito di; Shen, C.; Mollinger, J.; Bastemeijer, J.; Bossche, A. (2011)
      Article
      Accés obert
      Fabrication of nanochannels is drawing considerable interest due to its broad applications in nanobiotechnology (e.g. biomolecular sensing and single DNA manipulation). Nanochannels offer distinct advantages in allowing a ...
    • DNA-catalyzed Henry reaction in pure water and the striking influence of organic buffer systems 

      Häring, Marleen; Pérez Madrigal, Maria del Mar; Kühbeck, Dennis; Pettignano, Asja; Quignard, Françoise; Díaz Díaz, David (2015-03-04)
      Article
      Accés obert
      In this manuscript we report a critical evaluation of the ability of natural DNA to mediate the nitroaldol (Henry) reaction at physiological temperature in pure water. Under these conditions, no background reaction took ...
    • Eines biotecnològiques digitals, desenvolupament i implantació a l'aula d'una activitat 

      Sans Sànchez, Adrià (Universitat Politècnica de Catalunya, 2023-06-14)
      Projecte Final de Màster Oficial
      Accés obert
      L'objectiu d'aquest treball és explorar l'ús d'eines digitals i Realitat Virtual en l'educació, especialment en el camp de la biotecnologia. Per complementar-ho, s'elabora una activitat que s'acabarà implementant a l'aula ...
    • Enhanced sensitivity and contrast with bimodal atomic force microscopy with small and ultra-small amplitudes in ambient conditions 

      Santos Hernández, Sergio (2013-12-02)
      Article
      Accés obert
      Here, we introduce bimodal atomic force microscopy operated with sub-nm and ultra-small, i.e., sub-angstrom, first and second mode amplitudes in ambient conditions. We show how the tip can be made to oscillate in the ...
    • Error estimation in environmental DNA targets quantification due to PCR efficiencies differences between real samples and standards 

      Pérez, Leonardo Martín; Fittipaldi Gustavino, Mariana; Adrados Ruiz, Barbara; Morató Farreras, Jordi; Codony Iglesias, Francesc (2013-11-01)
      Article
      Accés obert