Exploració per autor "Unzueta, Ugutz"
Ara es mostren els items 1-6 de 6
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Bottom-Up instructive quality control in the biofabrication of smart protein materials
Rueda, Fabian; Cespedes, Maria Virtudes; Cochinillo, Oscar; Sanchez Chardi, Alejandro; Seras Franzoso, Joaquin; Cubarsí Morera, Rafael; Gallardo, Alberto; Pesarrodona, Mireia; Ferrer Miralles, Neus; Daura, Xavier; Vazquez Gómez, Esther; García Fruitós, Elena; Mangues, Ramón; Unzueta, Ugutz; Villaverde, A. (2015-10)
Article
Accés obert -
CXCR4(+)-targeted protein nanoparticles produced in the food-grade bacterium Lactococcus lactis
Cano Garrido, Olivia; Cespedes, Maria Virtudes; Unzueta, Ugutz; Roldan, Monica; Cubarsí Morera, Rafael; Vazquez Gómez, Esther; García Fruitós, Elena; Villaverde Corrales, Antonio Pedro (2016-09-01)
Article
Accés obertLactococcus lactis is a Gram-positive (endotoxin-free) food-grade bacteria exploited as alternative to Escherichia coli for recombinant protein production. We have explored here for the first time the ability of this ... -
Endosomal escape of protein nanoparticles engineered through humanized histidine-rich peptides
Lopez Laguna, Hector; Cubarsí Morera, Rafael; Unzueta, Ugutz; Mangues, Ramón; Vazquez, Esther; Villaverde, Antonio (2019-12-27)
Article
Accés obertPoly-histidine peptides such as H6 (HHHHHH) are used in protein biotechnologies as purification tags, pro- tein-assembling agents and endosomal-escape entities. The pleiotropic properties of such peptides make them appealing ... -
Internalization and kinetics of nuclear migration of protein-only, arginine-rich nanoparticles
Vázquez, Esther; Cubarsí Morera, Rafael; Unzueta, Ugutz; Roldán, Mónica; Domingo-Espín, Joan; Ferrer-Miralles, Neus; Villaverde, Antonio (2010-12)
Article
Accés restringit per política de l'editorialUnderstanding the intracellular trafficking of nanoparticles internalized by mammalian cells is a critical issue in nanomedicine, intimately linked to therapeutic applications but also to toxicity concerns. While the uptake ... -
Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP
Unzueta, Ugutz; Roldán Molina, Mónica; Pesarrodona, Mireia; Benítez Iglesias, Raúl; Sanchez Chardi, Alejandro; Conchillo, Oscar; Mangues, Ramón; Villaverde, Antonio; Vazquez Gómez, Esther (Elsevier, 2020-02-03)
Article
Accés obertFluorescent proteins are useful imaging and theranostic agents, but their potential superiority over alternative dyes is weakened by substantial photobleaching under irradiation. Enhancing protein photostability has been ... -
Switching cell penetrating and CXCR4-binding activities of nanoscale-organized arginine-rich peptides
Teixeira De Pinho Favaro, Marianna; Serna, Naroa; Sanchez Garcia, Laura; Cubarsí Morera, Rafael; Roldan, Monica; Sanchez Chardi, Alejandro; Unzueta, Ugutz; Mangues, Ramón; Ferrer Miralles, Neus; Rodrigues Azzoni, Adriano; Vazquez Gómez, Esther; Villaverde, Antonio (2018-08-01)
Article
Accés obertArginine-rich protein motifs have been described as potent cell-penetrating peptides (CPPs) but also as rather specific ligands of the cell surface chemokine receptor CXCR4, involved in the infection by the human ...