Now showing items 1-2 of 2

  • Modification of microbial polymalic acid with hydrophobic amino acids for drug-releasing nanoparticles 

    Lanz, Alberto; García Álvarez, Montserrat; Portilla Arias, Jose Antonio; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Holler, Eggehard; Ljubimova, Julia Y.; Muñoz Guerra, Sebastián (2012-08-14)
    Article
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    Microbial poly( β , L -malic acid) was modifi ed with either L -leucine ethyl ester (L) or L -phenylalanine methyl ester (F) to produce amphiphylic copolymers. The degradation of these copolymers in aqueous buffer took ...
  • Poly(methyl malate) nanoparticles: formation, degradation, and encapsulation of anticancer drugs 

    Lanz, Alberto; García Álvarez, Montserrat; Portilla Arias, Jose Antonio; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Patil, Rameshwar; Holler, Eggehard; Ljubimova, Julia Y.; Muñoz Guerra, Sebastián (2011-10-10)
    Article
    Restricted access - publisher's policy
    PMLA nanoparticles with diameters of 150–250nm are prepared, and their hydrolytic degradation is studied under physiological conditions. Degradation occurs by hydrolysis of the side chain methyl ester followed by cleavage ...