Now showing items 4-6 of 6

  • Relaxation dynamics and frequency response of a noisy cell signaling network 

    Rue Queralt, Pau; Pons Rivero, Antonio Javier; Domedel Puig, Núria; García Ojalvo, Jordi (2010-12-30)
    Article
    Open Access
    We investigate the dynamics of cell signaling using an experimentally based Boolean model of the human fibroblast signal transduction network. We determine via systematic numerical simulations the relaxation dynamics of ...
  • Simulation methods with extended stability for stiff biochemical Kinetics 

    Rue Queralt, Pau; Villà-Freixa, Jordi; Burrage, Kevin (2010-08-11)
    Article
    Open Access
    Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical systems involves a ...
  • The histone variant macroH2A is an epigenetic regulator of key developmental genes 

    Buschbeck, Markus; Uribesalgo, Iris; Wibowo, Indra; Rue Queralt, Pau; Martín, David; Gutiérrez, Arantxa; Morey, Lluís; Guigó, Roderic; López-Schier; Di Croce, Luciano (2009-09-06)
    Article
    Restricted access - publisher's policy
    The histone variants macroH2A1 1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the physiological function of macroH2A proteins on autosomes is poorly understood. Microarray-based ...