Exploració per tema "Genetics"

Ara es mostren els items 21-40 de 58

    • Estrategias de análisis de interacciones gen-ambiente en estudios GWAS 

      Alonso Aguado, Maria Henar (Universitat Politècnica de Catalunya, 2014-06)
      Projecte Final de Màster Oficial
      Accés restringit per decisió de l'autor
      Se realizaron estudios de asociación para encontrar los SNP de susceptibilidad para el riesgo de cáncer colorrectal y la interacción con el Índice de Masa Corporal (IMC). Este estudio de epidemiología genética está compuesto ...

    • Estudio de la dinámica de un ecosistema marino 

      Castellví Linde, Gloria (Universitat Politècnica de Catalunya, 2016-05)
      Treball Final de Grau
      Accés obert
      Realitzat a/amb:   Institut de Ciències del Mar
      La aportación de los Sistemas dinámicos al estudio de modelos en Biología ha sido importante ya desde los primeros ejemplos asociados a dinámica de poblaciones: modelos depredador-presa, competición entre especies y muchos ...

    • Functional protein-based nanomaterial produced in microorganisms recognized as safe: A new platform for biotechnology 

      Cano Garrido, Olivia; Sanchez Chardi, Alejandro; Parés, Silvia; Giró, Irene; Tatkiewicz, Witold I.; Ferrer Miralles, Neus; Ratera, Imma; Natalello, Antonino; Cubarsí Morera, Rafael; Veciana Miró, Jaume; Bach, Alex; Villaverde Corrales, Antonio Pedro; Arís, Anna; García Fruitós, Elena (2016-10-01)
      Article
      Accés obert
      Inclusion bodies (IBs) are protein-based nanoparticles formed in Escherichia coli through stereospecific aggregation processes during the overexpression of recombinant proteins. In the last years, it has been shown that ...

    • Genetic toggle-switch in a multicellular feedback control strategy 

      Cristòbal, Enric (Universitat Politècnica de Catalunya, 2019-07-09)
      Treball Final de Grau
      Accés obert
      Synthetic biology is a field of study placed on the bioengineering world aiming to rationally engineer the biological processes that take place inside the living organisms to endow cells and organisms with new useful ...

    • Germline genetic contribution to the immune landscape of cancer 

      Sayaman, Rosalyn W.; Saad, Mohamad; Thorsson, Vésteinn; Hu, Donglei; Hendrickx, Wouter; Roelands, Jessica; Porta Pardo, Eduard; Mokrab, Younes; Farshidfar, Farshad; Kirchhoff, Tomas; Sweis, Randy F.; Bathe, Oliver F.; Heimann, Carolina; Campbell, Michael J.; Stretch, Cynthia; Huntsman, Scott; Graff, Rebecca E.; Syed, Najeeb; Radvanyi, Laszlo; Shelley, Simon; Wolf, Denise; Marincola, Francesco M.; Ceccarelli, Michele; Galon, Jérôme; Ziv, Elad; Bedognetti, Davide (Elsevier, 2021-02)
      Article
      Accés obert
      Understanding the contribution of the host’s genetic background to cancer immunity may lead to improved stratification for immunotherapy and to the identification of novel therapeutic targets. We investigated the effect ...

    • Graphlet laplacians for topology-function and topology-disease relationships 

      Windels, Sam F L; Malod Dognin, Noël; Pržulj, Nataša (Oxford University Press (OUP), 2019-12-15)
      Article
      Accés obert
      Motivation Laplacian matrices capture the global structure of networks and are widely used to study biological networks. However, the local structure of the network around a node can also capture biological information. ...

    • High-throughput prediction of the impact of genetic variability on drug sensitivity and resistance patterns for clinically relevant epidermal growth factor receptor mutations from atomistic simulations 

      Suriñach, Aristarc; Hospital, Adam; Westermaier, Yvonne; Jorda, Luis; Orozco Ruiz, Sergi; Andrio, Pau; Gelpi, Josep (American Chemical Society, 2022)
      Article
      Accés obert
      Mutations in the kinase domain of the epidermal growth factor receptor (EGFR) can be drivers of cancer and also trigger drug resistance in patients receiving chemotherapy treatment based on kinase inhibitors. A priori ...

    • Interpreting new born genomes 

      Brenner, Steven E. (Barcelona Supercomputing Center, 2018)
      Text en actes de congrés
      Accés obert

    • Long-lasting salt bridges provide the anchoring mechanism of oncogenic kirsten rat sarcoma proteins at cell membranes 

      Huixia, Lu; Martí Rabassa, Jordi (2020-11-10)
      Article
      Accés obert
      RAS proteins work as GDP-GTP binary switches and regulate cytoplasmic signaling networks that are able to control several cellular processes, playing an essential role in signal transduction pathways involved in cell growth, ...

    • Looking for transcription factor binding sites 

      Roca Lacostena, Jordi (Universitat Politècnica de Catalunya, 2015-10)
      Projecte Final de Màster Oficial
      Accés restringit per acord de confidencialitat
      Realitzat a/amb:   Institut d'Investigació en Intel·ligència Artificial

    • Machine learning for data homogenization and genomic sequence processing 

      Barrabés I Torrella, Miriam (Universitat Politècnica de Catalunya, 2022-06-27)
      Treball Final de Grau
      Accés restringit per decisió de l'autor

    • Mapping the genetic component of gene expression variance with Mixed Graphical Markov Models : the marginal case 

      Coca Mariné, Ignacio (Universitat Politècnica de Catalunya, 2015-10)
      Projecte Final de Màster Oficial
      Accés obert
      Realitzat a/amb:   Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut
      En este trabajo desarrollamos la teoría de los modelos gráficos mixtos de Markov (GMMs), y en concreto los modelos heterogéneos. Aplicamos esta teoría a la búsqueda de marcadores génicos que afectan a la varianza de la ...

    • Mathematical topics in phylogenetics 

      Pérez De Los Cobos Hermosa, Cassius Manuel (Universitat Politècnica de Catalunya, 2017-03)
      Projecte Final de Màster Oficial
      Accés obert
      Realitzat a/amb:   Max F. Perutz Laboratories / Universität Wien
      An evolutionary process is frequently modeled as a sequence of the four bases A,C,G,T, each of them changing independently following a Markov process. The main goal of this project are two: first of all, we wanted to ...

    • Maximum likelihood estimation of linkage disequilibrium 

      Masós Torró, Clàudia (Universitat Politècnica de Catalunya, 2015-05)
      Treball Final de Grau
      Accés restringit per decisió de l'autor
      This project develops the theory of linkage disequilibrium (LD) estimation for a pair of genetic markers using the maximum likelihood function of a multinomial distribution. Basic statistics for LD such as $D$, $D'$ and ...

    • Métodos para la determinación de genotipos a partir de datos de microarrays de genotipado 

      Rodríguez Casado, Clara Isabel (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2014-06)
      Projecte Final de Màster Oficial
      Accés restringit per decisió de l'autor
      Este proyecto se enmarca en el análisis de datos de un estudio de epidemiología genética que tiene por objetivo final identificar genes asociados al desarrollo de cáncer. Se analizarán datos genéticos obtenidos en un estudio ...

    • Modelització matemàtica del creixement d'Alexandrium minutum en aigües litorals 

      Colas Navarro, Martina (Universitat Politècnica de Catalunya, 2022-07)
      Treball Final de Grau
      Accés obert
      This project aims to find out the goodness of Agent-Based Models for modeling ecological microbial systems. For doing it, first, it is done a study of the methodology, and then, it is modeled a microbial example system to ...

    • Modelling "calçots" (Allium cepa L.) growth by Gompertz function 

      Simó, Joan; Plans, Marçal; Casañas, Francesc; Sabaté, Jose (Institut d'Estadística de Catalunya, 2013)
      Article
      Accés obert
      "Calçots" are the second-year resprouts of the "Ceba Blanca Tardana de Lleida" landrace of onions. The evolution of three "calçots" populations has been modeled to help farmers to plan the optimal time to harvest. Four ...

    • Modelling and analysis of crayfish competition 

      Solà Lorente, Jaume (Universitat Politècnica de Catalunya, 2015-09)
      Treball Final de Grau
      Accés restringit per acord de confidencialitat
      Realitzat a/amb:   Technische Universität München. Fakultät für Mathematik

    • Modelling within-host viral evolution with cross-immunity. Numerical simulation of the model 

      Van Laarhoven, Narani (Universitat Politècnica de Catalunya, 2014-07)
      Projecte Final de Màster Oficial
      Accés restringit per acord de confidencialitat

    • Mortality of NBA Players: risk factors and comparison with the general US population 

      Martínez García, Jose Antonio; Langohr, Klaus; Felipo, Julián; Casals Toquero, Martí (2019-02)
      Article
      Accés obert
      Concerns have been raised recently by players’ associations regarding the risk of death among retired players. Using a retrospective cohort study, we analyzed factors associated with the mortality of National Basketball ...