• Clinical trial designs using CompARE. An on-line exploratory tool for investigators 

      Gómez Mateu, Moisés; Gómez Melis, Guadalupe (2017-03)
      Report de recerca
      Accés obert
      Conclusions from randomized clinical trials (RCT) rely primarily on the primary endpoint (PE) chosen at the design stage of the study. There should generally be only one PE which should be able to provide the most clinically ...
    • Composite endpoints for stent cardiovascular clinical trials 

      Gómez Mateu, Moisés (Universitat Politècnica de Catalunya, 2011)
      Projecte Final de Màster Oficial
      Accés obert
      Quan es comparen dos tractaments A i B en base a un anàlisi de supervivència sovint s'utilitza com punt final (endpoint) d'interès l'esdeveniment E* format per la unió de dos o més esdeveniments. Per exemple, en estudis ...
    • Extensions and applications of CompARE : web platform to select the primary endpoint in a randomized clinical trial 

      Gómez Mateu, Moisés; Gómez Melis, Guadalupe (Fundación Mapfre, 2015)
      Text en actes de congrés
      Accés obert
      We present CompARE, a web platform that computes how more efficient is to use a composite endpoint instead of one of its components. CompARE is based on the Asymptotic Relative Efficiency (ARE) method develop by Gómez and ...
    • Recommendations to choose the primary endpoint in cardiovascular clinical trials 

      Gómez Melis, Guadalupe; Gómez Mateu, Moisés; Dafni, Urania (2013)
      Report de recerca
      Accés obert
      Background – A composite endpoint is often used as the primary endpoint to assess the efficacy of a new treatment in randomized clinical trials (RCT). In cardiovascular trials, the often rare event of the relevant primary ...
    • The asymptotic relative efficiency and the ratio of sample sizes when testing two different null hypotheses 

      Gómez Melis, Guadalupe; Gómez Mateu, Moisés (Institut d'Estadística de Catalunya, 2014-06)
      Article
      Accés obert
      Composite endpoints, consisting of the union of two or more outcomes, are often used as the primary endpoint in time-to-event randomized clinical trials. Previously, Gómez and Lagakos provided a method to guide the decision ...
    • Time of progression to osteopenia/osteoporosis in chronically HIV-infected patients: screening DXA scan 

      Negredo, Eugènia; Bonjoch, Anna; Gómez Mateu, Moisés; Estany, Carla; Puig, Jordi; Pérez Álvarez, Nuria; Rosales, Joaquim; di Gregorio, Silvana; del Rio, Luis; Gómez Melis, Guadalupe; Clotet, Bonaventura (2012-10-08)
      Article
      Accés obert
      Algorithms for bone mineral density (BMD) management in HIV-infected patients are lacking. Our objective was to assess how often a dual-energy x-ray absorptiometry (DXA) scan should be performed by assessing time of ...
    • Young biostatisticians in Spain: career or race? 

      Lorenzo Arribas, Altea; Martínez Silva, Isabel; Gómez Mateu, Moisés; Pérez Álvarez, Nuria; Perpiñán Fabuel, Hèctor; Valero Coppin, Oliver (Sociedad de Estadística e Investigación Operativa (SEIO), 2013-10)
      Article
      Accés restringit per política de l'editorial
      Challenges and new opportunities for the integration of biostatisticians in multidisciplinary teams are a major concern in the field. New forms of broader training in the life sciences, collaborations with other scientists, ...